CHARACTERISTICS OF PITUITARY-OPVARIAN-ADRENAL AXIS IN ADOLESCENT GIRLS WITH HYPERPROLACTINEMIA OF VARIOUS GENESIS

The article presents the results of examination of 97 adolescent girls (mean age 14,96 ± 0,26 years) with hyperprolactinemia (PRL levels above 700 IU/ml): 30 adolescent girls with pituitary microprolactinoma (mean age 14,7 ± 3.2 years) and 67 adolescent girls with functional hyperprolactinemia (mean...

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Autores principales:	A. V. Labygina, L. M. Lazareva, L. V. Suturina, L. I. Kolesnikova, L. F. Sholokhov, E. E. Khramova, T. L. Olifirenko, E. S. Shaulskaya
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2012
Materias:	hyperprolactinemia macroprolactinemia impaired of sexual development menstrual cycle garuenie hyperandrogenism anovulation Science Q
Acceso en línea:	https://doaj.org/article/8003ca5177bd4b2399d9bf5c9b6fb77d
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spelling	oai:doaj.org-article:8003ca5177bd4b2399d9bf5c9b6fb77d2021-11-23T06:14:19ZCHARACTERISTICS OF PITUITARY-OPVARIAN-ADRENAL AXIS IN ADOLESCENT GIRLS WITH HYPERPROLACTINEMIA OF VARIOUS GENESIS2541-94202587-9596https://doaj.org/article/8003ca5177bd4b2399d9bf5c9b6fb77d2012-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/850https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The article presents the results of examination of 97 adolescent girls (mean age 14,96 ± 0,26 years) with hyperprolactinemia (PRL levels above 700 IU/ml): 30 adolescent girls with pituitary microprolactinoma (mean age 14,7 ± 3.2 years) and 67 adolescent girls with functional hyperprolactinemia (mean age 14,6 ± 3,4 years). The control group included 35 healthy adolescent girls (mean age 15,8 ± 0,89 years). Hyperprolactinemia (tumor and non-neoplastic) in puberty leads to disorders of sexual development and ovarian-menstrual cycle, followed by neurological symptoms. Elevated concentrations of testosterone, cortisol, DHEA, 17-OH-progesterone and LH/FSH ratio were shown in adolescents with hyperprolactinemia compared to the control group. Macroprolactinemia was estimated in 16,4—20 % of girls with hyperprolactinemia.A. V. LabyginaL. M. LazarevaL. V. SuturinaL. I. KolesnikovaL. F. SholokhovE. E. KhramovaT. L. OlifirenkoE. S. ShaulskayaScientific Сentre for Family Health and Human Reproduction Problemsarticlehyperprolactinemiamacroprolactinemiaimpaired of sexual developmentmenstrual cycle garueniehyperandrogenismanovulationScienceQRUActa Biomedica Scientifica, Vol 0, Iss 3(1), Pp 36-40 (2012)
institution	DOAJ
collection	DOAJ
language	RU
topic	hyperprolactinemia macroprolactinemia impaired of sexual development menstrual cycle garuenie hyperandrogenism anovulation Science Q
spellingShingle	hyperprolactinemia macroprolactinemia impaired of sexual development menstrual cycle garuenie hyperandrogenism anovulation Science Q A. V. Labygina L. M. Lazareva L. V. Suturina L. I. Kolesnikova L. F. Sholokhov E. E. Khramova T. L. Olifirenko E. S. Shaulskaya CHARACTERISTICS OF PITUITARY-OPVARIAN-ADRENAL AXIS IN ADOLESCENT GIRLS WITH HYPERPROLACTINEMIA OF VARIOUS GENESIS
description	The article presents the results of examination of 97 adolescent girls (mean age 14,96 ± 0,26 years) with hyperprolactinemia (PRL levels above 700 IU/ml): 30 adolescent girls with pituitary microprolactinoma (mean age 14,7 ± 3.2 years) and 67 adolescent girls with functional hyperprolactinemia (mean age 14,6 ± 3,4 years). The control group included 35 healthy adolescent girls (mean age 15,8 ± 0,89 years). Hyperprolactinemia (tumor and non-neoplastic) in puberty leads to disorders of sexual development and ovarian-menstrual cycle, followed by neurological symptoms. Elevated concentrations of testosterone, cortisol, DHEA, 17-OH-progesterone and LH/FSH ratio were shown in adolescents with hyperprolactinemia compared to the control group. Macroprolactinemia was estimated in 16,4—20 % of girls with hyperprolactinemia.
format	article
author	A. V. Labygina L. M. Lazareva L. V. Suturina L. I. Kolesnikova L. F. Sholokhov E. E. Khramova T. L. Olifirenko E. S. Shaulskaya
author_facet	A. V. Labygina L. M. Lazareva L. V. Suturina L. I. Kolesnikova L. F. Sholokhov E. E. Khramova T. L. Olifirenko E. S. Shaulskaya
author_sort	A. V. Labygina
title	CHARACTERISTICS OF PITUITARY-OPVARIAN-ADRENAL AXIS IN ADOLESCENT GIRLS WITH HYPERPROLACTINEMIA OF VARIOUS GENESIS
title_short	CHARACTERISTICS OF PITUITARY-OPVARIAN-ADRENAL AXIS IN ADOLESCENT GIRLS WITH HYPERPROLACTINEMIA OF VARIOUS GENESIS
title_full	CHARACTERISTICS OF PITUITARY-OPVARIAN-ADRENAL AXIS IN ADOLESCENT GIRLS WITH HYPERPROLACTINEMIA OF VARIOUS GENESIS
title_fullStr	CHARACTERISTICS OF PITUITARY-OPVARIAN-ADRENAL AXIS IN ADOLESCENT GIRLS WITH HYPERPROLACTINEMIA OF VARIOUS GENESIS
title_full_unstemmed	CHARACTERISTICS OF PITUITARY-OPVARIAN-ADRENAL AXIS IN ADOLESCENT GIRLS WITH HYPERPROLACTINEMIA OF VARIOUS GENESIS
title_sort	characteristics of pituitary-opvarian-adrenal axis in adolescent girls with hyperprolactinemia of various genesis
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2012
url	https://doaj.org/article/8003ca5177bd4b2399d9bf5c9b6fb77d
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CHARACTERISTICS OF PITUITARY-OPVARIAN-ADRENAL AXIS IN ADOLESCENT GIRLS WITH HYPERPROLACTINEMIA OF VARIOUS GENESIS

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