Brain adiponectin signaling controls peripheral insulin response in Drosophila
Circulating adiponectin controls sensitivity to insulin in tissues. Here, Arquier et al. show that adiponectin receptor activity in neurons of the Drosophila brain controls insulin response in peripheral tissues via juvenile hormone signaling.
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Nature Portfolio
2021
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oai:doaj.org-article:80074213c66844b5b08eaab47537804d2021-12-02T17:26:56ZBrain adiponectin signaling controls peripheral insulin response in Drosophila10.1038/s41467-021-25940-62041-1723https://doaj.org/article/80074213c66844b5b08eaab47537804d2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25940-6https://doaj.org/toc/2041-1723Circulating adiponectin controls sensitivity to insulin in tissues. Here, Arquier et al. show that adiponectin receptor activity in neurons of the Drosophila brain controls insulin response in peripheral tissues via juvenile hormone signaling.Nathalie ArquierMarianne BjordalPhilippe HammannLauriane KuhnPierre LéopoldNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021) |
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Science Q Nathalie Arquier Marianne Bjordal Philippe Hammann Lauriane Kuhn Pierre Léopold Brain adiponectin signaling controls peripheral insulin response in Drosophila |
description |
Circulating adiponectin controls sensitivity to insulin in tissues. Here, Arquier et al. show that adiponectin receptor activity in neurons of the Drosophila brain controls insulin response in peripheral tissues via juvenile hormone signaling. |
format |
article |
author |
Nathalie Arquier Marianne Bjordal Philippe Hammann Lauriane Kuhn Pierre Léopold |
author_facet |
Nathalie Arquier Marianne Bjordal Philippe Hammann Lauriane Kuhn Pierre Léopold |
author_sort |
Nathalie Arquier |
title |
Brain adiponectin signaling controls peripheral insulin response in Drosophila |
title_short |
Brain adiponectin signaling controls peripheral insulin response in Drosophila |
title_full |
Brain adiponectin signaling controls peripheral insulin response in Drosophila |
title_fullStr |
Brain adiponectin signaling controls peripheral insulin response in Drosophila |
title_full_unstemmed |
Brain adiponectin signaling controls peripheral insulin response in Drosophila |
title_sort |
brain adiponectin signaling controls peripheral insulin response in drosophila |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/80074213c66844b5b08eaab47537804d |
work_keys_str_mv |
AT nathaliearquier brainadiponectinsignalingcontrolsperipheralinsulinresponseindrosophila AT mariannebjordal brainadiponectinsignalingcontrolsperipheralinsulinresponseindrosophila AT philippehammann brainadiponectinsignalingcontrolsperipheralinsulinresponseindrosophila AT laurianekuhn brainadiponectinsignalingcontrolsperipheralinsulinresponseindrosophila AT pierreleopold brainadiponectinsignalingcontrolsperipheralinsulinresponseindrosophila |
_version_ |
1718380797951475712 |