Ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies

Optimization of antiviral therapy can be crucial in the management of Ebola virus outbreaks. Here, Madelain et al. use an integrative mathematical model to correlate the dose and the time of treatment initiation with survival rate, enhanced immune response and viral clearance.

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Autores principales:	Vincent Madelain, Sylvain Baize, Frédéric Jacquot, Stéphanie Reynard, Alexandra Fizet, Stephane Barron, Caroline Solas, Bruno Lacarelle, Caroline Carbonnelle, France Mentré, Hervé Raoul, Xavier de Lamballerie, Jérémie Guedj
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8007c9d9b043441c879ab95a1e9f13f9
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spelling	oai:doaj.org-article:8007c9d9b043441c879ab95a1e9f13f92021-12-02T16:56:41ZEbola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies10.1038/s41467-018-06215-z2041-1723https://doaj.org/article/8007c9d9b043441c879ab95a1e9f13f92018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06215-zhttps://doaj.org/toc/2041-1723Optimization of antiviral therapy can be crucial in the management of Ebola virus outbreaks. Here, Madelain et al. use an integrative mathematical model to correlate the dose and the time of treatment initiation with survival rate, enhanced immune response and viral clearance.Vincent MadelainSylvain BaizeFrédéric JacquotStéphanie ReynardAlexandra FizetStephane BarronCaroline SolasBruno LacarelleCaroline CarbonnelleFrance MentréHervé RaoulXavier de LamballerieJérémie GuedjNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Vincent Madelain Sylvain Baize Frédéric Jacquot Stéphanie Reynard Alexandra Fizet Stephane Barron Caroline Solas Bruno Lacarelle Caroline Carbonnelle France Mentré Hervé Raoul Xavier de Lamballerie Jérémie Guedj Ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies
description	Optimization of antiviral therapy can be crucial in the management of Ebola virus outbreaks. Here, Madelain et al. use an integrative mathematical model to correlate the dose and the time of treatment initiation with survival rate, enhanced immune response and viral clearance.
format	article
author	Vincent Madelain Sylvain Baize Frédéric Jacquot Stéphanie Reynard Alexandra Fizet Stephane Barron Caroline Solas Bruno Lacarelle Caroline Carbonnelle France Mentré Hervé Raoul Xavier de Lamballerie Jérémie Guedj
author_facet	Vincent Madelain Sylvain Baize Frédéric Jacquot Stéphanie Reynard Alexandra Fizet Stephane Barron Caroline Solas Bruno Lacarelle Caroline Carbonnelle France Mentré Hervé Raoul Xavier de Lamballerie Jérémie Guedj
author_sort	Vincent Madelain
title	Ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies
title_short	Ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies
title_full	Ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies
title_fullStr	Ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies
title_full_unstemmed	Ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies
title_sort	ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/8007c9d9b043441c879ab95a1e9f13f9
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Ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies

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