Hemodynamics-driven mathematical model of first and second heart sound generation.

<h4>New & noteworthy</h4>To the best of our knowledge, this is the first hemodynamic-based heart sound generation model embedded in a complete real-time computational model of the cardiovascular system. Simulated heart sounds are similar to experimental and clinical measurements, bot...

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Autores principales:	Mehrdad Shahmohammadi, Hongxing Luo, Philip Westphal, Richard N Cornelussen, Frits W Prinzen, Tammo Delhaas
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/80083483b95a4f168981eebd1b3e164b
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spelling	oai:doaj.org-article:80083483b95a4f168981eebd1b3e164b2021-12-02T19:57:45ZHemodynamics-driven mathematical model of first and second heart sound generation.1553-734X1553-735810.1371/journal.pcbi.1009361https://doaj.org/article/80083483b95a4f168981eebd1b3e164b2021-09-01T00:00:00Zhttps://doi.org/10.1371/journal.pcbi.1009361https://doaj.org/toc/1553-734Xhttps://doaj.org/toc/1553-7358<h4>New & noteworthy</h4>To the best of our knowledge, this is the first hemodynamic-based heart sound generation model embedded in a complete real-time computational model of the cardiovascular system. Simulated heart sounds are similar to experimental and clinical measurements, both quantitatively and qualitatively. Our model can be used to investigate the relationships between heart sound acoustic features and hemodynamic factors/anatomical parameters.Mehrdad ShahmohammadiHongxing LuoPhilip WestphalRichard N CornelussenFrits W PrinzenTammo DelhaasPublic Library of Science (PLoS)articleBiology (General)QH301-705.5ENPLoS Computational Biology, Vol 17, Iss 9, p e1009361 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Mehrdad Shahmohammadi Hongxing Luo Philip Westphal Richard N Cornelussen Frits W Prinzen Tammo Delhaas Hemodynamics-driven mathematical model of first and second heart sound generation.
description	<h4>New & noteworthy</h4>To the best of our knowledge, this is the first hemodynamic-based heart sound generation model embedded in a complete real-time computational model of the cardiovascular system. Simulated heart sounds are similar to experimental and clinical measurements, both quantitatively and qualitatively. Our model can be used to investigate the relationships between heart sound acoustic features and hemodynamic factors/anatomical parameters.
format	article
author	Mehrdad Shahmohammadi Hongxing Luo Philip Westphal Richard N Cornelussen Frits W Prinzen Tammo Delhaas
author_facet	Mehrdad Shahmohammadi Hongxing Luo Philip Westphal Richard N Cornelussen Frits W Prinzen Tammo Delhaas
author_sort	Mehrdad Shahmohammadi
title	Hemodynamics-driven mathematical model of first and second heart sound generation.
title_short	Hemodynamics-driven mathematical model of first and second heart sound generation.
title_full	Hemodynamics-driven mathematical model of first and second heart sound generation.
title_fullStr	Hemodynamics-driven mathematical model of first and second heart sound generation.
title_full_unstemmed	Hemodynamics-driven mathematical model of first and second heart sound generation.
title_sort	hemodynamics-driven mathematical model of first and second heart sound generation.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/80083483b95a4f168981eebd1b3e164b
work_keys_str_mv	AT mehrdadshahmohammadi hemodynamicsdrivenmathematicalmodeloffirstandsecondheartsoundgeneration AT hongxingluo hemodynamicsdrivenmathematicalmodeloffirstandsecondheartsoundgeneration AT philipwestphal hemodynamicsdrivenmathematicalmodeloffirstandsecondheartsoundgeneration AT richardncornelussen hemodynamicsdrivenmathematicalmodeloffirstandsecondheartsoundgeneration AT fritswprinzen hemodynamicsdrivenmathematicalmodeloffirstandsecondheartsoundgeneration AT tammodelhaas hemodynamicsdrivenmathematicalmodeloffirstandsecondheartsoundgeneration
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Hemodynamics-driven mathematical model of first and second heart sound generation.

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