ZFR coordinates crosstalk between RNA decay and transcription in innate immunity

Type I interferon signaling is critical for the control of infection. Here the authors show that zinc finger RNA-binding protein (ZFR) can control type I interferon responses, and that this control is itself regulated by distinct ZFR truncation patterns that differ between monocytes and macrophages.

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Autores principales:	Nazmul Haque, Ryota Ouda, Chao Chen, Keiko Ozato, J. Robert Hogg
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/800c0cdfa17d4fdea1b4e6b2de7afff6
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spelling	oai:doaj.org-article:800c0cdfa17d4fdea1b4e6b2de7afff62021-12-02T17:32:33ZZFR coordinates crosstalk between RNA decay and transcription in innate immunity10.1038/s41467-018-03326-52041-1723https://doaj.org/article/800c0cdfa17d4fdea1b4e6b2de7afff62018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03326-5https://doaj.org/toc/2041-1723Type I interferon signaling is critical for the control of infection. Here the authors show that zinc finger RNA-binding protein (ZFR) can control type I interferon responses, and that this control is itself regulated by distinct ZFR truncation patterns that differ between monocytes and macrophages.Nazmul HaqueRyota OudaChao ChenKeiko OzatoJ. Robert HoggNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nazmul Haque Ryota Ouda Chao Chen Keiko Ozato J. Robert Hogg ZFR coordinates crosstalk between RNA decay and transcription in innate immunity
description	Type I interferon signaling is critical for the control of infection. Here the authors show that zinc finger RNA-binding protein (ZFR) can control type I interferon responses, and that this control is itself regulated by distinct ZFR truncation patterns that differ between monocytes and macrophages.
format	article
author	Nazmul Haque Ryota Ouda Chao Chen Keiko Ozato J. Robert Hogg
author_facet	Nazmul Haque Ryota Ouda Chao Chen Keiko Ozato J. Robert Hogg
author_sort	Nazmul Haque
title	ZFR coordinates crosstalk between RNA decay and transcription in innate immunity
title_short	ZFR coordinates crosstalk between RNA decay and transcription in innate immunity
title_full	ZFR coordinates crosstalk between RNA decay and transcription in innate immunity
title_fullStr	ZFR coordinates crosstalk between RNA decay and transcription in innate immunity
title_full_unstemmed	ZFR coordinates crosstalk between RNA decay and transcription in innate immunity
title_sort	zfr coordinates crosstalk between rna decay and transcription in innate immunity
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/800c0cdfa17d4fdea1b4e6b2de7afff6
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ZFR coordinates crosstalk between RNA decay and transcription in innate immunity

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