ZFR coordinates crosstalk between RNA decay and transcription in innate immunity

Type I interferon signaling is critical for the control of infection. Here the authors show that zinc finger RNA-binding protein (ZFR) can control type I interferon responses, and that this control is itself regulated by distinct ZFR truncation patterns that differ between monocytes and macrophages.

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Auteurs principaux: Nazmul Haque, Ryota Ouda, Chao Chen, Keiko Ozato, J. Robert Hogg
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/800c0cdfa17d4fdea1b4e6b2de7afff6
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