Prevalence and risk factors for faecal carriage of multidrug resistant Escherichia coli among slaughterhouse workers

Abstract The increasing occurrence of antimicrobial-resistant Escherichia coli in human and animal population has become a global public health problem that requires immediate intervention. We aimed to investigate prevalence and risk factors for faecal carriage of drug-resistant E. coli among slaugh...

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Autores principales:	Mabel Kamweli Aworh, Oluwadamilola Abiodun-Adewusi, Nwando Mba, Birgitte Helwigh, Rene S. Hendriksen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/800d2a3943b1425ba5b6e30899ec564f
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spelling	oai:doaj.org-article:800d2a3943b1425ba5b6e30899ec564f2021-12-02T17:45:17ZPrevalence and risk factors for faecal carriage of multidrug resistant Escherichia coli among slaughterhouse workers10.1038/s41598-021-92819-32045-2322https://doaj.org/article/800d2a3943b1425ba5b6e30899ec564f2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-92819-3https://doaj.org/toc/2045-2322Abstract The increasing occurrence of antimicrobial-resistant Escherichia coli in human and animal population has become a global public health problem that requires immediate intervention. We aimed to investigate prevalence and risk factors for faecal carriage of drug-resistant E. coli among slaughterhouse workers. We conducted this cross-sectional study among 118 apparently healthy workers in the largest slaughterhouses in Abuja and Lagos from July to December 2020. E. coli was isolated from stool samples of slaughterhouse workers and antimicrobial susceptibility testing performed using the Kirby-Bauer disk diffusion method. Multi-drug resistance (MDR) was defined as resistance to three or more classes of antibiotics. Majority were males: 88.1% (n = 104), aged > 41 years: 28.8% (n = 34), married: 70.3% (n = 83), and were butchers: 53.4% (n = 63). Prevalence of MDR E. coli was 50% (n = 59), highest among butchers compared to slaughterhouse cleaners. Of 75 E. coli isolates identified, 25.3% (n = 19) were ESBL producers; 78.7% (n = 59) were MDR. Keeping animals (p = 0.01); eating at the slaughterhouse (p = 0.03) and collecting waste (p = 0.02) remained independent risk factors for acquiring MDR E. coli. Prevalence of resistant E. coli was highest among butchers and associated with keeping animals at home, eating at work, and waste-collection. Hand-hygiene and responsible use of antibiotics among slaughterhouse workers should be encouraged.Mabel Kamweli AworhOluwadamilola Abiodun-AdewusiNwando MbaBirgitte HelwighRene S. HendriksenNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Mabel Kamweli Aworh Oluwadamilola Abiodun-Adewusi Nwando Mba Birgitte Helwigh Rene S. Hendriksen Prevalence and risk factors for faecal carriage of multidrug resistant Escherichia coli among slaughterhouse workers
description	Abstract The increasing occurrence of antimicrobial-resistant Escherichia coli in human and animal population has become a global public health problem that requires immediate intervention. We aimed to investigate prevalence and risk factors for faecal carriage of drug-resistant E. coli among slaughterhouse workers. We conducted this cross-sectional study among 118 apparently healthy workers in the largest slaughterhouses in Abuja and Lagos from July to December 2020. E. coli was isolated from stool samples of slaughterhouse workers and antimicrobial susceptibility testing performed using the Kirby-Bauer disk diffusion method. Multi-drug resistance (MDR) was defined as resistance to three or more classes of antibiotics. Majority were males: 88.1% (n = 104), aged > 41 years: 28.8% (n = 34), married: 70.3% (n = 83), and were butchers: 53.4% (n = 63). Prevalence of MDR E. coli was 50% (n = 59), highest among butchers compared to slaughterhouse cleaners. Of 75 E. coli isolates identified, 25.3% (n = 19) were ESBL producers; 78.7% (n = 59) were MDR. Keeping animals (p = 0.01); eating at the slaughterhouse (p = 0.03) and collecting waste (p = 0.02) remained independent risk factors for acquiring MDR E. coli. Prevalence of resistant E. coli was highest among butchers and associated with keeping animals at home, eating at work, and waste-collection. Hand-hygiene and responsible use of antibiotics among slaughterhouse workers should be encouraged.
format	article
author	Mabel Kamweli Aworh Oluwadamilola Abiodun-Adewusi Nwando Mba Birgitte Helwigh Rene S. Hendriksen
author_facet	Mabel Kamweli Aworh Oluwadamilola Abiodun-Adewusi Nwando Mba Birgitte Helwigh Rene S. Hendriksen
author_sort	Mabel Kamweli Aworh
title	Prevalence and risk factors for faecal carriage of multidrug resistant Escherichia coli among slaughterhouse workers
title_short	Prevalence and risk factors for faecal carriage of multidrug resistant Escherichia coli among slaughterhouse workers
title_full	Prevalence and risk factors for faecal carriage of multidrug resistant Escherichia coli among slaughterhouse workers
title_fullStr	Prevalence and risk factors for faecal carriage of multidrug resistant Escherichia coli among slaughterhouse workers
title_full_unstemmed	Prevalence and risk factors for faecal carriage of multidrug resistant Escherichia coli among slaughterhouse workers
title_sort	prevalence and risk factors for faecal carriage of multidrug resistant escherichia coli among slaughterhouse workers
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/800d2a3943b1425ba5b6e30899ec564f
work_keys_str_mv	AT mabelkamweliaworh prevalenceandriskfactorsforfaecalcarriageofmultidrugresistantescherichiacoliamongslaughterhouseworkers AT oluwadamilolaabiodunadewusi prevalenceandriskfactorsforfaecalcarriageofmultidrugresistantescherichiacoliamongslaughterhouseworkers AT nwandomba prevalenceandriskfactorsforfaecalcarriageofmultidrugresistantescherichiacoliamongslaughterhouseworkers AT birgittehelwigh prevalenceandriskfactorsforfaecalcarriageofmultidrugresistantescherichiacoliamongslaughterhouseworkers AT reneshendriksen prevalenceandriskfactorsforfaecalcarriageofmultidrugresistantescherichiacoliamongslaughterhouseworkers
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Prevalence and risk factors for faecal carriage of multidrug resistant Escherichia coli among slaughterhouse workers

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