Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set

Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set

Genetic variants might exert their functional effects via influencing molecular interaction. Here, the authors present a resource featuring almost 28,000 annotations describing the effect of small sequence changes on physical protein interactions, curated by IMEx Consortium curators.

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Autores principales: The IMEx Consortium Curators, N. del-Toro, M. Duesbury, M. Koch, L. Perfetto, A. Shrivastava, D. Ochoa, O. Wagih, J. Piñero, M. Kotlyar, C. Pastrello, P. Beltrao, L. I. Furlong, I. Jurisica, H. Hermjakob, S. Orchard, P. Porras
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/800e57758e8442bf894f27e692090476
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spelling oai:doaj.org-article:800e57758e8442bf894f27e6920904762021-12-02T15:35:03ZCapturing variation impact on molecular interactions in the IMEx Consortium mutations data set10.1038/s41467-018-07709-62041-1723https://doaj.org/article/800e57758e8442bf894f27e6920904762019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07709-6https://doaj.org/toc/2041-1723Genetic variants might exert their functional effects via influencing molecular interaction. Here, the authors present a resource featuring almost 28,000 annotations describing the effect of small sequence changes on physical protein interactions, curated by IMEx Consortium curators.The IMEx Consortium CuratorsN. del-ToroM. DuesburyM. KochL. PerfettoA. ShrivastavaD. OchoaO. WagihJ. PiñeroM. KotlyarC. PastrelloP. BeltraoL. I. FurlongI. JurisicaH. HermjakobS. OrchardP. PorrasNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
The IMEx Consortium Curators
N. del-Toro
M. Duesbury
M. Koch
L. Perfetto
A. Shrivastava
D. Ochoa
O. Wagih
J. Piñero
M. Kotlyar
C. Pastrello
P. Beltrao
L. I. Furlong
I. Jurisica
H. Hermjakob
S. Orchard
P. Porras
Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set
description Genetic variants might exert their functional effects via influencing molecular interaction. Here, the authors present a resource featuring almost 28,000 annotations describing the effect of small sequence changes on physical protein interactions, curated by IMEx Consortium curators.
format article
author The IMEx Consortium Curators
N. del-Toro
M. Duesbury
M. Koch
L. Perfetto
A. Shrivastava
D. Ochoa
O. Wagih
J. Piñero
M. Kotlyar
C. Pastrello
P. Beltrao
L. I. Furlong
I. Jurisica
H. Hermjakob
S. Orchard
P. Porras
author_facet The IMEx Consortium Curators
N. del-Toro
M. Duesbury
M. Koch
L. Perfetto
A. Shrivastava
D. Ochoa
O. Wagih
J. Piñero
M. Kotlyar
C. Pastrello
P. Beltrao
L. I. Furlong
I. Jurisica
H. Hermjakob
S. Orchard
P. Porras
author_sort The IMEx Consortium Curators
title Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set
title_short Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set
title_full Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set
title_fullStr Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set
title_full_unstemmed Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set
title_sort capturing variation impact on molecular interactions in the imex consortium mutations data set
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/800e57758e8442bf894f27e692090476
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