COMPARISON OF RESAZURIN AND MTT METHODS ON STUDIES OF CITOTOXICITY IN HUMAN TUMOR CELL LINES

A study was carried comparing the resazurina and MTT methods as indicators of indirect measure of cellular survival applied to valuated cytotoxic activity in order to assess the suitability of each of the two detection systems. The comparison was made through the valuation of cytotoxicity on three c...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Linamaría ESCOBAR M., Augusto RIVERA, Fabio A. ARISTIZÁBAL G.
Formato:	article
Lenguaje:	EN
Publicado:	Universidad de Antioquia 2010
Materias:	Doxorubicin MTT resazurine cellular viability. Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675
Acceso en línea:	https://doaj.org/article/80119a60620a441caf0ab7d39a949241
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:80119a60620a441caf0ab7d39a949241
record_format	dspace
spelling	oai:doaj.org-article:80119a60620a441caf0ab7d39a9492412021-11-19T04:14:38ZCOMPARISON OF RESAZURIN AND MTT METHODS ON STUDIES OF CITOTOXICITY IN HUMAN TUMOR CELL LINES0121-40042145-2660https://doaj.org/article/80119a60620a441caf0ab7d39a9492412010-03-01T00:00:00Zhttps://revistas.udea.edu.co/index.php/vitae/article/view/4977https://doaj.org/toc/0121-4004https://doaj.org/toc/2145-2660A study was carried comparing the resazurina and MTT methods as indicators of indirect measure of cellular survival applied to valuated cytotoxic activity in order to assess the suitability of each of the two detection systems. The comparison was made through the valuation of cytotoxicity on three cell lines derived from human tumors: HEp-2, HT-29 and HeLa, evaluating three synthetic compounds during a treatment period of 48 hours using as a reference activity Doxorubicin HCl. The results obtained by the two methods showed a similar performance under the conditions tested in cell linesLinamaría ESCOBAR M.Augusto RIVERAFabio A. ARISTIZÁBAL G.Universidad de AntioquiaarticleDoxorubicinMTTresazurinecellular viability.Food processing and manufactureTP368-456Pharmaceutical industryHD9665-9675ENVitae, Vol 17, Iss 1 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Doxorubicin MTT resazurine cellular viability. Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675
spellingShingle	Doxorubicin MTT resazurine cellular viability. Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675 Linamaría ESCOBAR M. Augusto RIVERA Fabio A. ARISTIZÁBAL G. COMPARISON OF RESAZURIN AND MTT METHODS ON STUDIES OF CITOTOXICITY IN HUMAN TUMOR CELL LINES
description	A study was carried comparing the resazurina and MTT methods as indicators of indirect measure of cellular survival applied to valuated cytotoxic activity in order to assess the suitability of each of the two detection systems. The comparison was made through the valuation of cytotoxicity on three cell lines derived from human tumors: HEp-2, HT-29 and HeLa, evaluating three synthetic compounds during a treatment period of 48 hours using as a reference activity Doxorubicin HCl. The results obtained by the two methods showed a similar performance under the conditions tested in cell lines
format	article
author	Linamaría ESCOBAR M. Augusto RIVERA Fabio A. ARISTIZÁBAL G.
author_facet	Linamaría ESCOBAR M. Augusto RIVERA Fabio A. ARISTIZÁBAL G.
author_sort	Linamaría ESCOBAR M.
title	COMPARISON OF RESAZURIN AND MTT METHODS ON STUDIES OF CITOTOXICITY IN HUMAN TUMOR CELL LINES
title_short	COMPARISON OF RESAZURIN AND MTT METHODS ON STUDIES OF CITOTOXICITY IN HUMAN TUMOR CELL LINES
title_full	COMPARISON OF RESAZURIN AND MTT METHODS ON STUDIES OF CITOTOXICITY IN HUMAN TUMOR CELL LINES
title_fullStr	COMPARISON OF RESAZURIN AND MTT METHODS ON STUDIES OF CITOTOXICITY IN HUMAN TUMOR CELL LINES
title_full_unstemmed	COMPARISON OF RESAZURIN AND MTT METHODS ON STUDIES OF CITOTOXICITY IN HUMAN TUMOR CELL LINES
title_sort	comparison of resazurin and mtt methods on studies of citotoxicity in human tumor cell lines
publisher	Universidad de Antioquia
publishDate	2010
url	https://doaj.org/article/80119a60620a441caf0ab7d39a949241
work_keys_str_mv	AT linamariaescobarm comparisonofresazurinandmttmethodsonstudiesofcitotoxicityinhumantumorcelllines AT augustorivera comparisonofresazurinandmttmethodsonstudiesofcitotoxicityinhumantumorcelllines AT fabioaaristizabalg comparisonofresazurinandmttmethodsonstudiesofcitotoxicityinhumantumorcelllines
_version_	1718420461438631936

COMPARISON OF RESAZURIN AND MTT METHODS ON STUDIES OF CITOTOXICITY IN HUMAN TUMOR CELL LINES

Ejemplares similares