The Role of ACE2 Receptors of the Olfactory System in Anosmia in COVID-19: An Overview

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes coronavirus disease 2019 (COVID-19). The latest data show that more than 211.7 million people were infected and more than 4.4 million deaths have been reported. The illness presents a wide range of symptoms, rangin...

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Autores principales: Mohammad Javad Nasr, Ali Alizadeh Khatir, Arefeh Babazadeh, Soheil Ebrahimpour
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Publicado: Hindawi Limited 2021
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spelling oai:doaj.org-article:80143a5f5f564c94b8b18566db6c79402021-11-15T01:19:47ZThe Role of ACE2 Receptors of the Olfactory System in Anosmia in COVID-19: An Overview2090-186010.1155/2021/5776801https://doaj.org/article/80143a5f5f564c94b8b18566db6c79402021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/5776801https://doaj.org/toc/2090-1860Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes coronavirus disease 2019 (COVID-19). The latest data show that more than 211.7 million people were infected and more than 4.4 million deaths have been reported. The illness presents a wide range of symptoms, ranging from mild to severe. Mild symptoms include cough, fever, dyspnea, fatigue, myalgia and arthralgia, anosmia, and dysgeusia. Furthermore, this virus can affect the central nervous system (CNS) and present a range of mild to severe nervous symptoms, from headache and dysphoria to loss of consciousness, coma, paralysis, and acute cerebrovascular disease. The virus can enter nonneuronal cells of the olfactory epithelium and cause a complete loss of smell. Anosmia and hyposmia are commonly reported in clinics, and being asymptomatic or showing mild symptoms can be primary symptoms in early infected persons. Dysgeusia/hypogeusia is another symptom presented with anosmia/hyposmia. In this article, we reviewed the articles of anosmia and suggested a possible mechanism for this.Mohammad Javad NasrAli Alizadeh KhatirArefeh BabazadehSoheil EbrahimpourHindawi LimitedarticleNeurology. Diseases of the nervous systemRC346-429ENNeurology Research International, Vol 2021 (2021)
institution DOAJ
collection DOAJ
language EN
topic Neurology. Diseases of the nervous system
RC346-429
spellingShingle Neurology. Diseases of the nervous system
RC346-429
Mohammad Javad Nasr
Ali Alizadeh Khatir
Arefeh Babazadeh
Soheil Ebrahimpour
The Role of ACE2 Receptors of the Olfactory System in Anosmia in COVID-19: An Overview
description Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes coronavirus disease 2019 (COVID-19). The latest data show that more than 211.7 million people were infected and more than 4.4 million deaths have been reported. The illness presents a wide range of symptoms, ranging from mild to severe. Mild symptoms include cough, fever, dyspnea, fatigue, myalgia and arthralgia, anosmia, and dysgeusia. Furthermore, this virus can affect the central nervous system (CNS) and present a range of mild to severe nervous symptoms, from headache and dysphoria to loss of consciousness, coma, paralysis, and acute cerebrovascular disease. The virus can enter nonneuronal cells of the olfactory epithelium and cause a complete loss of smell. Anosmia and hyposmia are commonly reported in clinics, and being asymptomatic or showing mild symptoms can be primary symptoms in early infected persons. Dysgeusia/hypogeusia is another symptom presented with anosmia/hyposmia. In this article, we reviewed the articles of anosmia and suggested a possible mechanism for this.
format article
author Mohammad Javad Nasr
Ali Alizadeh Khatir
Arefeh Babazadeh
Soheil Ebrahimpour
author_facet Mohammad Javad Nasr
Ali Alizadeh Khatir
Arefeh Babazadeh
Soheil Ebrahimpour
author_sort Mohammad Javad Nasr
title The Role of ACE2 Receptors of the Olfactory System in Anosmia in COVID-19: An Overview
title_short The Role of ACE2 Receptors of the Olfactory System in Anosmia in COVID-19: An Overview
title_full The Role of ACE2 Receptors of the Olfactory System in Anosmia in COVID-19: An Overview
title_fullStr The Role of ACE2 Receptors of the Olfactory System in Anosmia in COVID-19: An Overview
title_full_unstemmed The Role of ACE2 Receptors of the Olfactory System in Anosmia in COVID-19: An Overview
title_sort role of ace2 receptors of the olfactory system in anosmia in covid-19: an overview
publisher Hindawi Limited
publishDate 2021
url https://doaj.org/article/80143a5f5f564c94b8b18566db6c7940
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