Actomyosin meshwork mechanosensing enables tissue shape to orient cell force

Large-scale tissue reorganization requires the generation of directional tension, which requires orientation of the cytoskeleton. Here Chanetet al. alter tissue shape and tension in the Drosophilaembryo to show that geometric and mechanical constraints act as cues to orient the cytoskeleton and tens...

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Autores principales: Soline Chanet, Callie J. Miller, Eeshit Dhaval Vaishnav, Bard Ermentrout, Lance A. Davidson, Adam C. Martin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/80150cadc5a14fb087a6ee30c3090a55
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Sumario:Large-scale tissue reorganization requires the generation of directional tension, which requires orientation of the cytoskeleton. Here Chanetet al. alter tissue shape and tension in the Drosophilaembryo to show that geometric and mechanical constraints act as cues to orient the cytoskeleton and tension.