Role of tumor necrosis factor-α in the human systemic endotoxin-induced transcriptome.

Role of tumor necrosis factor-α in the human systemic endotoxin-induced transcriptome.

TNFα has been implicated in the pathogenesis of various inflammatory diseases. Different strategies to inhibit TNFα in patients with sepsis and chronic inflammatory conditions have shown contrasting outcomes. Although TNFα inhibitors are widely used in clinical practice, the impact of TNFα antagonis...

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Bibliographic Details
Main Authors: Brendon P Scicluna, Cornelis van 't Veer, Max Nieuwdorp, Karen Felsmann, Britta Wlotzka, Erik S G Stroes, Tom van der Poll
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/80163fdce7f3411da037a891373af1ab
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