A sexually dimorphic pre-stressed translational signature in CA3 pyramidal neurons of BDNF Val66Met mice

Animals’ response to acute stress is known to be influenced by sex and genetics. Here the authors performed RNA-seq on actively translated mRNAs in hippocampal CA3 neurons in mice, and document the effects of sex and genotype (i.e., BDNF Val66Met) on acute stress-induced gene expression.

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Autores principales: Jordan Marrocco, Gordon H. Petty, Mariel B. Ríos, Jason D. Gray, Joshua F. Kogan, Elizabeth M. Waters, Eric F. Schmidt, Francis S. Lee, Bruce S. McEwen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/801b66d7a1be477d9f8b4a7aaf7b868e
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spelling oai:doaj.org-article:801b66d7a1be477d9f8b4a7aaf7b868e2021-12-02T15:38:50ZA sexually dimorphic pre-stressed translational signature in CA3 pyramidal neurons of BDNF Val66Met mice10.1038/s41467-017-01014-42041-1723https://doaj.org/article/801b66d7a1be477d9f8b4a7aaf7b868e2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01014-4https://doaj.org/toc/2041-1723Animals’ response to acute stress is known to be influenced by sex and genetics. Here the authors performed RNA-seq on actively translated mRNAs in hippocampal CA3 neurons in mice, and document the effects of sex and genotype (i.e., BDNF Val66Met) on acute stress-induced gene expression.Jordan MarroccoGordon H. PettyMariel B. RíosJason D. GrayJoshua F. KoganElizabeth M. WatersEric F. SchmidtFrancis S. LeeBruce S. McEwenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jordan Marrocco
Gordon H. Petty
Mariel B. Ríos
Jason D. Gray
Joshua F. Kogan
Elizabeth M. Waters
Eric F. Schmidt
Francis S. Lee
Bruce S. McEwen
A sexually dimorphic pre-stressed translational signature in CA3 pyramidal neurons of BDNF Val66Met mice
description Animals’ response to acute stress is known to be influenced by sex and genetics. Here the authors performed RNA-seq on actively translated mRNAs in hippocampal CA3 neurons in mice, and document the effects of sex and genotype (i.e., BDNF Val66Met) on acute stress-induced gene expression.
format article
author Jordan Marrocco
Gordon H. Petty
Mariel B. Ríos
Jason D. Gray
Joshua F. Kogan
Elizabeth M. Waters
Eric F. Schmidt
Francis S. Lee
Bruce S. McEwen
author_facet Jordan Marrocco
Gordon H. Petty
Mariel B. Ríos
Jason D. Gray
Joshua F. Kogan
Elizabeth M. Waters
Eric F. Schmidt
Francis S. Lee
Bruce S. McEwen
author_sort Jordan Marrocco
title A sexually dimorphic pre-stressed translational signature in CA3 pyramidal neurons of BDNF Val66Met mice
title_short A sexually dimorphic pre-stressed translational signature in CA3 pyramidal neurons of BDNF Val66Met mice
title_full A sexually dimorphic pre-stressed translational signature in CA3 pyramidal neurons of BDNF Val66Met mice
title_fullStr A sexually dimorphic pre-stressed translational signature in CA3 pyramidal neurons of BDNF Val66Met mice
title_full_unstemmed A sexually dimorphic pre-stressed translational signature in CA3 pyramidal neurons of BDNF Val66Met mice
title_sort sexually dimorphic pre-stressed translational signature in ca3 pyramidal neurons of bdnf val66met mice
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/801b66d7a1be477d9f8b4a7aaf7b868e
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