Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism
Anti-resorptive bone therapies also inhibit bone formation, as osteoclasts secrete factors that stimulate bone formation by osteoblasts. Here, the authors identify osteoclast-secreted factors that couple bone resorption to bone formation in healthy subjects, and show that osteoclast-derived DPP4 may...
Enregistré dans:
Auteurs principaux: | Megan M. Weivoda, Chee Kian Chew, David G. Monroe, Joshua N. Farr, Elizabeth J. Atkinson, Jennifer R. Geske, Brittany Eckhardt, Brianne Thicke, Ming Ruan, Amanda J. Tweed, Louise K. McCready, Robert A. Rizza, Aleksey Matveyenko, Moustapha Kassem, Thomas Levin Andersen, Adrian Vella, Matthew T. Drake, Bart L. Clarke, Merry Jo Oursler, Sundeep Khosla |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2020
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/801d47b97fd94e109d4d6b51b08d8de3 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Osteoblast-osteoclast co-cultures: A systematic review and map of available literature.
par: Stefan J A Remmers, et autres
Publié: (2021) -
Osteoblast-osteoclast co-cultures: A systematic review and map of available literature
par: Stefan J. A. Remmers, et autres
Publié: (2021) -
Optogenetic activation of Plexin-B1 reveals contact repulsion between osteoclasts and osteoblasts
par: Abhijit Deb Roy, et autres
Publié: (2017) -
Influence of ARHGEF3 and RHOA knockdown on ACTA2 and other genes in osteoblasts and osteoclasts.
par: Benjamin H Mullin, et autres
Publié: (2014) -
Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk
par: Lijun Wang, et autres
Publié: (2020)