Methanol-dependent Escherichia coli strains with a complete ribulose monophosphate cycle

The engineering of methanol-dependent growth in Escherichia coli is challenging. Here, the authors predict and experimentally validate methanol-dependent strains with a complete RuMP cycle and high potential for the development of a methylotrophic platform organism.

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Autores principales:	Philipp Keller, Elad Noor, Fabian Meyer, Michael A. Reiter, Stanislav Anastassov, Patrick Kiefer, Julia A. Vorholt
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8021e3394aee40be935ad830142840df
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spelling	oai:doaj.org-article:8021e3394aee40be935ad830142840df2021-12-02T16:49:46ZMethanol-dependent Escherichia coli strains with a complete ribulose monophosphate cycle10.1038/s41467-020-19235-52041-1723https://doaj.org/article/8021e3394aee40be935ad830142840df2020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19235-5https://doaj.org/toc/2041-1723The engineering of methanol-dependent growth in Escherichia coli is challenging. Here, the authors predict and experimentally validate methanol-dependent strains with a complete RuMP cycle and high potential for the development of a methylotrophic platform organism.Philipp KellerElad NoorFabian MeyerMichael A. ReiterStanislav AnastassovPatrick KieferJulia A. VorholtNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Philipp Keller Elad Noor Fabian Meyer Michael A. Reiter Stanislav Anastassov Patrick Kiefer Julia A. Vorholt Methanol-dependent Escherichia coli strains with a complete ribulose monophosphate cycle
description	The engineering of methanol-dependent growth in Escherichia coli is challenging. Here, the authors predict and experimentally validate methanol-dependent strains with a complete RuMP cycle and high potential for the development of a methylotrophic platform organism.
format	article
author	Philipp Keller Elad Noor Fabian Meyer Michael A. Reiter Stanislav Anastassov Patrick Kiefer Julia A. Vorholt
author_facet	Philipp Keller Elad Noor Fabian Meyer Michael A. Reiter Stanislav Anastassov Patrick Kiefer Julia A. Vorholt
author_sort	Philipp Keller
title	Methanol-dependent Escherichia coli strains with a complete ribulose monophosphate cycle
title_short	Methanol-dependent Escherichia coli strains with a complete ribulose monophosphate cycle
title_full	Methanol-dependent Escherichia coli strains with a complete ribulose monophosphate cycle
title_fullStr	Methanol-dependent Escherichia coli strains with a complete ribulose monophosphate cycle
title_full_unstemmed	Methanol-dependent Escherichia coli strains with a complete ribulose monophosphate cycle
title_sort	methanol-dependent escherichia coli strains with a complete ribulose monophosphate cycle
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/8021e3394aee40be935ad830142840df
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Methanol-dependent Escherichia coli strains with a complete ribulose monophosphate cycle

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