BCL-2 Expression in AML Patients over 65 Years: Impact on Outcomes across Different Therapeutic Strategies

BCL-2 Expression in AML Patients over 65 Years: Impact on Outcomes across Different Therapeutic Strategies

BCL-2 overexpression has been associated with resistance to chemotherapy and reduced survival in acute myeloid leukemia (AML), but few data are available in elderly patients, a subset accounting for majority of AML cases and with dismal prognosis. We retrospectively analyzed 113 AML patients aged ≥6...

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Autores principales: Mario Tiribelli, Angela Michelutti, Margherita Cavallin, Sara Di Giusto, Erica Simeone, Renato Fanin, Daniela Damiani
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
BCL-2
acute myeloid leukemia
elderly
prognosis
survival
Medicine
R
Acceso en línea:https://doaj.org/article/802def0c29cb45748f2e5f9266f5854a
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