Method to estimate relative risk using exposed proportion and case group data

Abstract A change in risk of an event occurring, which is affected with a factor, is a common issue in many research fields, and relative risk is widely used because of intuitive interpretation. Estimating relative risk has required data from two follow-up groups and can thus be cost and time consum...

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Autor principal:	Yoichi Yada
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/802f9c45ca7746679af8b7e60d31fa67
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spelling	oai:doaj.org-article:802f9c45ca7746679af8b7e60d31fa672021-12-02T16:06:49ZMethod to estimate relative risk using exposed proportion and case group data10.1038/s41598-017-02302-12045-2322https://doaj.org/article/802f9c45ca7746679af8b7e60d31fa672017-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-02302-1https://doaj.org/toc/2045-2322Abstract A change in risk of an event occurring, which is affected with a factor, is a common issue in many research fields, and relative risk is widely used because of intuitive interpretation. Estimating relative risk has required data from two follow-up groups and can thus be cost and time consuming. Subjects for whom an event occurred (case group) are often observed but generally analyzed in comparison to those for whom an event did not (control group); however, estimating relative risk using case group data without approximation is hindered. In this study, an obstacle to estimate relative risk using case control data is clarified as a mathematical expression and a new equation to estimate relative risk using the exposed proportion and case group data is proposed. The proposed equation is derived without using the Bayesian methods. A method to estimate the confidence interval for the proposed estimator is also provided. The usefulness of the proposed equation, which requires neither control nor follow-up groups, is demonstrated for both theoretical and real-life examples.Yoichi YadaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Yoichi Yada Method to estimate relative risk using exposed proportion and case group data
description	Abstract A change in risk of an event occurring, which is affected with a factor, is a common issue in many research fields, and relative risk is widely used because of intuitive interpretation. Estimating relative risk has required data from two follow-up groups and can thus be cost and time consuming. Subjects for whom an event occurred (case group) are often observed but generally analyzed in comparison to those for whom an event did not (control group); however, estimating relative risk using case group data without approximation is hindered. In this study, an obstacle to estimate relative risk using case control data is clarified as a mathematical expression and a new equation to estimate relative risk using the exposed proportion and case group data is proposed. The proposed equation is derived without using the Bayesian methods. A method to estimate the confidence interval for the proposed estimator is also provided. The usefulness of the proposed equation, which requires neither control nor follow-up groups, is demonstrated for both theoretical and real-life examples.
format	article
author	Yoichi Yada
author_facet	Yoichi Yada
author_sort	Yoichi Yada
title	Method to estimate relative risk using exposed proportion and case group data
title_short	Method to estimate relative risk using exposed proportion and case group data
title_full	Method to estimate relative risk using exposed proportion and case group data
title_fullStr	Method to estimate relative risk using exposed proportion and case group data
title_full_unstemmed	Method to estimate relative risk using exposed proportion and case group data
title_sort	method to estimate relative risk using exposed proportion and case group data
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/802f9c45ca7746679af8b7e60d31fa67
work_keys_str_mv	AT yoichiyada methodtoestimaterelativeriskusingexposedproportionandcasegroupdata
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Method to estimate relative risk using exposed proportion and case group data

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