Reduced Rank Regression-Derived Dietary Patterns Related to the Fatty Liver Index and Associations with Type 2 Diabetes Mellitus among Ghanaian Populations under Transition: The RODAM Study

The Fatty Liver Index (FLI) is a proxy for the steatotic component of non-alcoholic fatty liver disease (NAFLD). For sub-Saharan African populations, the contribution of dietary factors to the development of NAFLD in the etiology of type 2 diabetes mellitus (T2DM) remains to be clarified. We identif...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Tracy Bonsu Osei, Anne-Marieke van Dijk, Sjoerd Dingerink, Felix Patience Chilunga, Erik Beune, Karlijn Anna Catharina Meeks, Silver Bahendeka, Matthias Bernd Schulze, Charles Agyemang, Mary Nicolaou, Adriaan Georgius Holleboom, Ina Danquah
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	dietary pattern reduced rank regression fatty liver index type 2 diabetes mellitus non-alcoholic fatty liver disease Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/8034d776d2c043b8bebfc974d9b4e51b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:8034d776d2c043b8bebfc974d9b4e51b
record_format	dspace
spelling	oai:doaj.org-article:8034d776d2c043b8bebfc974d9b4e51b2021-11-25T18:33:08ZReduced Rank Regression-Derived Dietary Patterns Related to the Fatty Liver Index and Associations with Type 2 Diabetes Mellitus among Ghanaian Populations under Transition: The RODAM Study10.3390/nu131136792072-6643https://doaj.org/article/8034d776d2c043b8bebfc974d9b4e51b2021-10-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/3679https://doaj.org/toc/2072-6643The Fatty Liver Index (FLI) is a proxy for the steatotic component of non-alcoholic fatty liver disease (NAFLD). For sub-Saharan African populations, the contribution of dietary factors to the development of NAFLD in the etiology of type 2 diabetes mellitus (T2DM) remains to be clarified. We identified sex-specific dietary patterns (DPs) related to the FLI using reduced ranked regression (RRR) and evaluated the associations of these DPs with T2DM. This analysis used data from the RODAM, a multi-center cross-sectional study of Ghanaian populations living in Ghana and Europe. The daily intake frequencies of 30 food groups served as the predictor variables, while the FLI was the response variable. The odds ratios and 95% confidence intervals for T2DM were calculated per one standard deviation increase in the DP score using logistic regression. In males, the DP score explained 9.9% of the variation in their food intake and 16.0% of the variation in the FLI. This DP was characterized by high intakes of poultry, whole-grain cereals, coffee and tea, condiments, and potatoes, and the chance of T2DM was 45% higher per 1 DP score-SD (Model 2). Our results indicate that the intake of modernized foods was associated with proxies of NAFLD, possibly underlying the metabolic pathways to developing T2DM.Tracy Bonsu OseiAnne-Marieke van DijkSjoerd DingerinkFelix Patience ChilungaErik BeuneKarlijn Anna Catharina MeeksSilver BahendekaMatthias Bernd SchulzeCharles AgyemangMary NicolaouAdriaan Georgius HolleboomIna DanquahMDPI AGarticledietary patternreduced rank regressionfatty liver indextype 2 diabetes mellitusnon-alcoholic fatty liver diseaseNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 3679, p 3679 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	dietary pattern reduced rank regression fatty liver index type 2 diabetes mellitus non-alcoholic fatty liver disease Nutrition. Foods and food supply TX341-641
spellingShingle	dietary pattern reduced rank regression fatty liver index type 2 diabetes mellitus non-alcoholic fatty liver disease Nutrition. Foods and food supply TX341-641 Tracy Bonsu Osei Anne-Marieke van Dijk Sjoerd Dingerink Felix Patience Chilunga Erik Beune Karlijn Anna Catharina Meeks Silver Bahendeka Matthias Bernd Schulze Charles Agyemang Mary Nicolaou Adriaan Georgius Holleboom Ina Danquah Reduced Rank Regression-Derived Dietary Patterns Related to the Fatty Liver Index and Associations with Type 2 Diabetes Mellitus among Ghanaian Populations under Transition: The RODAM Study
description	The Fatty Liver Index (FLI) is a proxy for the steatotic component of non-alcoholic fatty liver disease (NAFLD). For sub-Saharan African populations, the contribution of dietary factors to the development of NAFLD in the etiology of type 2 diabetes mellitus (T2DM) remains to be clarified. We identified sex-specific dietary patterns (DPs) related to the FLI using reduced ranked regression (RRR) and evaluated the associations of these DPs with T2DM. This analysis used data from the RODAM, a multi-center cross-sectional study of Ghanaian populations living in Ghana and Europe. The daily intake frequencies of 30 food groups served as the predictor variables, while the FLI was the response variable. The odds ratios and 95% confidence intervals for T2DM were calculated per one standard deviation increase in the DP score using logistic regression. In males, the DP score explained 9.9% of the variation in their food intake and 16.0% of the variation in the FLI. This DP was characterized by high intakes of poultry, whole-grain cereals, coffee and tea, condiments, and potatoes, and the chance of T2DM was 45% higher per 1 DP score-SD (Model 2). Our results indicate that the intake of modernized foods was associated with proxies of NAFLD, possibly underlying the metabolic pathways to developing T2DM.
format	article
author	Tracy Bonsu Osei Anne-Marieke van Dijk Sjoerd Dingerink Felix Patience Chilunga Erik Beune Karlijn Anna Catharina Meeks Silver Bahendeka Matthias Bernd Schulze Charles Agyemang Mary Nicolaou Adriaan Georgius Holleboom Ina Danquah
author_facet	Tracy Bonsu Osei Anne-Marieke van Dijk Sjoerd Dingerink Felix Patience Chilunga Erik Beune Karlijn Anna Catharina Meeks Silver Bahendeka Matthias Bernd Schulze Charles Agyemang Mary Nicolaou Adriaan Georgius Holleboom Ina Danquah
author_sort	Tracy Bonsu Osei
title	Reduced Rank Regression-Derived Dietary Patterns Related to the Fatty Liver Index and Associations with Type 2 Diabetes Mellitus among Ghanaian Populations under Transition: The RODAM Study
title_short	Reduced Rank Regression-Derived Dietary Patterns Related to the Fatty Liver Index and Associations with Type 2 Diabetes Mellitus among Ghanaian Populations under Transition: The RODAM Study
title_full	Reduced Rank Regression-Derived Dietary Patterns Related to the Fatty Liver Index and Associations with Type 2 Diabetes Mellitus among Ghanaian Populations under Transition: The RODAM Study
title_fullStr	Reduced Rank Regression-Derived Dietary Patterns Related to the Fatty Liver Index and Associations with Type 2 Diabetes Mellitus among Ghanaian Populations under Transition: The RODAM Study
title_full_unstemmed	Reduced Rank Regression-Derived Dietary Patterns Related to the Fatty Liver Index and Associations with Type 2 Diabetes Mellitus among Ghanaian Populations under Transition: The RODAM Study
title_sort	reduced rank regression-derived dietary patterns related to the fatty liver index and associations with type 2 diabetes mellitus among ghanaian populations under transition: the rodam study
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/8034d776d2c043b8bebfc974d9b4e51b
work_keys_str_mv	AT tracybonsuosei reducedrankregressionderiveddietarypatternsrelatedtothefattyliverindexandassociationswithtype2diabetesmellitusamongghanaianpopulationsundertransitiontherodamstudy AT annemariekevandijk reducedrankregressionderiveddietarypatternsrelatedtothefattyliverindexandassociationswithtype2diabetesmellitusamongghanaianpopulationsundertransitiontherodamstudy AT sjoerddingerink reducedrankregressionderiveddietarypatternsrelatedtothefattyliverindexandassociationswithtype2diabetesmellitusamongghanaianpopulationsundertransitiontherodamstudy AT felixpatiencechilunga reducedrankregressionderiveddietarypatternsrelatedtothefattyliverindexandassociationswithtype2diabetesmellitusamongghanaianpopulationsundertransitiontherodamstudy AT erikbeune reducedrankregressionderiveddietarypatternsrelatedtothefattyliverindexandassociationswithtype2diabetesmellitusamongghanaianpopulationsundertransitiontherodamstudy AT karlijnannacatharinameeks reducedrankregressionderiveddietarypatternsrelatedtothefattyliverindexandassociationswithtype2diabetesmellitusamongghanaianpopulationsundertransitiontherodamstudy AT silverbahendeka reducedrankregressionderiveddietarypatternsrelatedtothefattyliverindexandassociationswithtype2diabetesmellitusamongghanaianpopulationsundertransitiontherodamstudy AT matthiasberndschulze reducedrankregressionderiveddietarypatternsrelatedtothefattyliverindexandassociationswithtype2diabetesmellitusamongghanaianpopulationsundertransitiontherodamstudy AT charlesagyemang reducedrankregressionderiveddietarypatternsrelatedtothefattyliverindexandassociationswithtype2diabetesmellitusamongghanaianpopulationsundertransitiontherodamstudy AT marynicolaou reducedrankregressionderiveddietarypatternsrelatedtothefattyliverindexandassociationswithtype2diabetesmellitusamongghanaianpopulationsundertransitiontherodamstudy AT adriaangeorgiusholleboom reducedrankregressionderiveddietarypatternsrelatedtothefattyliverindexandassociationswithtype2diabetesmellitusamongghanaianpopulationsundertransitiontherodamstudy AT inadanquah reducedrankregressionderiveddietarypatternsrelatedtothefattyliverindexandassociationswithtype2diabetesmellitusamongghanaianpopulationsundertransitiontherodamstudy
_version_	1718411027660406784

Reduced Rank Regression-Derived Dietary Patterns Related to the Fatty Liver Index and Associations with Type 2 Diabetes Mellitus among Ghanaian Populations under Transition: The RODAM Study

Ejemplares similares