Epithelial-Cell-Derived Extracellular Vesicles in Pathophysiology of Epithelial Injury and Repair in Chronic Rhinosinusitis: Connecting Immunology in Research Lab to Biomarkers in Clinics
Epithelial barrier disruption and failure of epithelial repair by aberrant epithelial-mesenchymal transition (EMT)-induced basal cells observed in nasal mucosa of chronic rhinosinusitis (CRS) are speculated to play important roles in disease pathophysiology. Microparticles (MPs) are a type of extrac...
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Main Authors: | Toru Takahashi, Robert P Schleimer |
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Format: | article |
Language: | EN |
Published: |
MDPI AG
2021
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Online Access: | https://doaj.org/article/8047dc7c0eaa4aa2966e9e333f8f492a |
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