COPD significantly increases cerebral and cardiovascular events in hypertensives

Abstract Essential hypertension and chronic obstructive pulmonary disease often coexist in the same patient. The aim of this study was to evaluate whether the addition of chronic obstructive pulmonary disease modifies the risk of cardiovascular events in hypertensives. We enrolled 1728 hypertensives...

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Autores principales:	Maria Perticone, Raffaele Maio, Benedetto Caroleo, Edoardo Suraci, Salvatore Corrao, Giorgio Sesti, Francesco Perticone
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8065a9a446a340a78c03f8f6464d82b5
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spelling	oai:doaj.org-article:8065a9a446a340a78c03f8f6464d82b52021-12-02T18:03:21ZCOPD significantly increases cerebral and cardiovascular events in hypertensives10.1038/s41598-021-86963-z2045-2322https://doaj.org/article/8065a9a446a340a78c03f8f6464d82b52021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-86963-zhttps://doaj.org/toc/2045-2322Abstract Essential hypertension and chronic obstructive pulmonary disease often coexist in the same patient. The aim of this study was to evaluate whether the addition of chronic obstructive pulmonary disease modifies the risk of cardiovascular events in hypertensives. We enrolled 1728 hypertensives. Study outcomes included fatal and non-fatal cardiovascular stroke and myocardial infarction, and cardiovascular death. During a mean follow-up of 57 months there were 205 major adverse cardiovascular events (2.47 per 100 pts/yr): cardiac (n117; 1.41 per 100 pts/yr) and cerebrovascular (n = 77; 0.93 per 100 pts/yr). In hypertensives with chronic obstructive pulmonary disease we observed a greater number of cardiovascular events than in hypertensives without respiratory disease (133 [5.55 per 100 pts/yr) vs 72 [1.22 per 100 pts/yr], respectively. The addition of chronic obstructive pulmonary disease to hypertension increased the incidence of total and non-fatal stroke of more than nine- (2.42 vs 0.32 per 100 pts/yr) and 11-fold (2.09 vs 0.22 per 100 pts/yr), respectively. The same trend was observed for total (2.88 vs 0.81 per 100 pts/yr) and non-fatal (2.67 vs 0.79 per 100 pts/y) myocardial infarction. The presence of chronic obstructive pulmonary disease in hypertensives significantly increases the risk of stroke, myocardial infarction and major adverse cardiovascular events.Maria PerticoneRaffaele MaioBenedetto CaroleoEdoardo SuraciSalvatore CorraoGiorgio SestiFrancesco PerticoneNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Maria Perticone Raffaele Maio Benedetto Caroleo Edoardo Suraci Salvatore Corrao Giorgio Sesti Francesco Perticone COPD significantly increases cerebral and cardiovascular events in hypertensives
description	Abstract Essential hypertension and chronic obstructive pulmonary disease often coexist in the same patient. The aim of this study was to evaluate whether the addition of chronic obstructive pulmonary disease modifies the risk of cardiovascular events in hypertensives. We enrolled 1728 hypertensives. Study outcomes included fatal and non-fatal cardiovascular stroke and myocardial infarction, and cardiovascular death. During a mean follow-up of 57 months there were 205 major adverse cardiovascular events (2.47 per 100 pts/yr): cardiac (n117; 1.41 per 100 pts/yr) and cerebrovascular (n = 77; 0.93 per 100 pts/yr). In hypertensives with chronic obstructive pulmonary disease we observed a greater number of cardiovascular events than in hypertensives without respiratory disease (133 [5.55 per 100 pts/yr) vs 72 [1.22 per 100 pts/yr], respectively. The addition of chronic obstructive pulmonary disease to hypertension increased the incidence of total and non-fatal stroke of more than nine- (2.42 vs 0.32 per 100 pts/yr) and 11-fold (2.09 vs 0.22 per 100 pts/yr), respectively. The same trend was observed for total (2.88 vs 0.81 per 100 pts/yr) and non-fatal (2.67 vs 0.79 per 100 pts/y) myocardial infarction. The presence of chronic obstructive pulmonary disease in hypertensives significantly increases the risk of stroke, myocardial infarction and major adverse cardiovascular events.
format	article
author	Maria Perticone Raffaele Maio Benedetto Caroleo Edoardo Suraci Salvatore Corrao Giorgio Sesti Francesco Perticone
author_facet	Maria Perticone Raffaele Maio Benedetto Caroleo Edoardo Suraci Salvatore Corrao Giorgio Sesti Francesco Perticone
author_sort	Maria Perticone
title	COPD significantly increases cerebral and cardiovascular events in hypertensives
title_short	COPD significantly increases cerebral and cardiovascular events in hypertensives
title_full	COPD significantly increases cerebral and cardiovascular events in hypertensives
title_fullStr	COPD significantly increases cerebral and cardiovascular events in hypertensives
title_full_unstemmed	COPD significantly increases cerebral and cardiovascular events in hypertensives
title_sort	copd significantly increases cerebral and cardiovascular events in hypertensives
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/8065a9a446a340a78c03f8f6464d82b5
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COPD significantly increases cerebral and cardiovascular events in hypertensives

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