Apcin inhibits the growth and invasion of glioblastoma cells and improves glioma sensitivity to temozolomide
Glioblastoma (GBM) is the most common malignant primary brain tumor, and GBM patients have a poor overall prognosis. CDC20 expression is increased in a variety of tumors and associated with temozolomide (TMZ) resistance in glioma cells. Apcin specifically binds to CDC20 to inhibit APC/C-CDC20 intera...
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| Main Authors: | , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Taylor & Francis Group
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/8068b882860c4b75a9f0f754d9266177 |
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