Mahanine exerts in vitro and in vivo antileishmanial activity by modulation of redox homeostasis
Abstract Earlier we have established a carbazole alkaloid (mahanine) isolated from an Indian edible medicinal plant as an anticancer agent with minimal effect on normal cells. Here we report for the first time that mahanine-treated drug resistant and sensitive virulent Leishmania donovani promastigo...
Guardado en:
Autores principales: | Saptarshi Roy, Devawati Dutta, Eswara M. Satyavarapu, Pawan K. Yadav, Chhabinath Mandal, Susanta Kar, Chitra Mandal |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/80716169997740029d4fce07680fcce7 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Synthetic oxoisoaporphine alkaloids: in vitro, in vivo and in silico assessment of antileishmanial activities.
por: Eduardo Sobarzo-Sánchez, et al.
Publicado: (2013) -
Synthesis, characterization, and mechanistic studies of a gold nanoparticle–amphotericin B covalent conjugate with enhanced antileishmanial efficacy and reduced cytotoxicity
por: Kumar P, et al.
Publicado: (2019) -
Design, synthesis and biological evaluation of N-oxide derivatives with potent in vivo antileishmanial activity.
por: Leandro da Costa Clementino, et al.
Publicado: (2021) -
Design, synthesis and biological evaluation of N-oxide derivatives with potent in vivo antileishmanial activity
por: Leandro da Costa Clementino, et al.
Publicado: (2021) -
Bioassay-based Corchorus capsularis L. leaf-derived β-sitosterol exerts antileishmanial effects against Leishmania donovani by targeting trypanothione reductase
por: Pijush Kanti Pramanik, et al.
Publicado: (2020)