Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis

Regulatory T (Treg) cells contribute to the anti-inflammatory response during atherogenesis. Here Gaddis et al. show that Apolipoprotein AI prevents the conversion of Treg cells into pro-atherogenic T follicular helper cells, and thus regulates the immune response during atherogenesis.

Guardado en:
Detalles Bibliográficos
Autores principales: Dalia E. Gaddis, Lindsey E. Padgett, Runpei Wu, Chantel McSkimming, Veronica Romines, Angela M. Taylor, Coleen A. McNamara, Mitchell Kronenberg, Shane Crotty, Michael J. Thomas, Mary G. Sorci-Thomas, Catherine C. Hedrick
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/8075bffece434699b9ec64bb663d89a5
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:8075bffece434699b9ec64bb663d89a5
record_format dspace
spelling oai:doaj.org-article:8075bffece434699b9ec64bb663d89a52021-12-02T14:40:45ZApolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis10.1038/s41467-018-03493-52041-1723https://doaj.org/article/8075bffece434699b9ec64bb663d89a52018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03493-5https://doaj.org/toc/2041-1723Regulatory T (Treg) cells contribute to the anti-inflammatory response during atherogenesis. Here Gaddis et al. show that Apolipoprotein AI prevents the conversion of Treg cells into pro-atherogenic T follicular helper cells, and thus regulates the immune response during atherogenesis.Dalia E. GaddisLindsey E. PadgettRunpei WuChantel McSkimmingVeronica RominesAngela M. TaylorColeen A. McNamaraMitchell KronenbergShane CrottyMichael J. ThomasMary G. Sorci-ThomasCatherine C. HedrickNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dalia E. Gaddis
Lindsey E. Padgett
Runpei Wu
Chantel McSkimming
Veronica Romines
Angela M. Taylor
Coleen A. McNamara
Mitchell Kronenberg
Shane Crotty
Michael J. Thomas
Mary G. Sorci-Thomas
Catherine C. Hedrick
Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis
description Regulatory T (Treg) cells contribute to the anti-inflammatory response during atherogenesis. Here Gaddis et al. show that Apolipoprotein AI prevents the conversion of Treg cells into pro-atherogenic T follicular helper cells, and thus regulates the immune response during atherogenesis.
format article
author Dalia E. Gaddis
Lindsey E. Padgett
Runpei Wu
Chantel McSkimming
Veronica Romines
Angela M. Taylor
Coleen A. McNamara
Mitchell Kronenberg
Shane Crotty
Michael J. Thomas
Mary G. Sorci-Thomas
Catherine C. Hedrick
author_facet Dalia E. Gaddis
Lindsey E. Padgett
Runpei Wu
Chantel McSkimming
Veronica Romines
Angela M. Taylor
Coleen A. McNamara
Mitchell Kronenberg
Shane Crotty
Michael J. Thomas
Mary G. Sorci-Thomas
Catherine C. Hedrick
author_sort Dalia E. Gaddis
title Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis
title_short Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis
title_full Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis
title_fullStr Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis
title_full_unstemmed Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis
title_sort apolipoprotein ai prevents regulatory to follicular helper t cell switching during atherosclerosis
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/8075bffece434699b9ec64bb663d89a5
work_keys_str_mv AT daliaegaddis apolipoproteinaipreventsregulatorytofollicularhelpertcellswitchingduringatherosclerosis
AT lindseyepadgett apolipoproteinaipreventsregulatorytofollicularhelpertcellswitchingduringatherosclerosis
AT runpeiwu apolipoproteinaipreventsregulatorytofollicularhelpertcellswitchingduringatherosclerosis
AT chantelmcskimming apolipoproteinaipreventsregulatorytofollicularhelpertcellswitchingduringatherosclerosis
AT veronicaromines apolipoproteinaipreventsregulatorytofollicularhelpertcellswitchingduringatherosclerosis
AT angelamtaylor apolipoproteinaipreventsregulatorytofollicularhelpertcellswitchingduringatherosclerosis
AT coleenamcnamara apolipoproteinaipreventsregulatorytofollicularhelpertcellswitchingduringatherosclerosis
AT mitchellkronenberg apolipoproteinaipreventsregulatorytofollicularhelpertcellswitchingduringatherosclerosis
AT shanecrotty apolipoproteinaipreventsregulatorytofollicularhelpertcellswitchingduringatherosclerosis
AT michaeljthomas apolipoproteinaipreventsregulatorytofollicularhelpertcellswitchingduringatherosclerosis
AT marygsorcithomas apolipoproteinaipreventsregulatorytofollicularhelpertcellswitchingduringatherosclerosis
AT catherinechedrick apolipoproteinaipreventsregulatorytofollicularhelpertcellswitchingduringatherosclerosis
_version_ 1718390183354695680