Predictors of responses to immune checkpoint blockade in advanced melanoma

The clinical management of metastatic melanoma requires predictors of the response to checkpoint blockade. Here, the authors use immunological assays to identify potential prognostic/predictive biomarkers in circulating blood cells and in tumor-infiltrating lymphocytes from patients with resected st...

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Autores principales:	N. Jacquelot, M. P. Roberti, D. P. Enot, S. Rusakiewicz, N. Ternès, S. Jegou, D. M. Woods, A. L. Sodré, M. Hansen, Y. Meirow, M. Sade-Feldman, A. Burra, S. S. Kwek, C. Flament, M. Messaoudene, C. P. M. Duong, L. Chen, B. S. Kwon, A. C. Anderson, V. K. Kuchroo, B. Weide, F. Aubin, C. Borg, S. Dalle, O. Beatrix, M. Ayyoub, B. Balme, G. Tomasic, A. M. Di Giacomo, M. Maio, D. Schadendorf, I. Melero, B. Dréno, A. Khammari, R. Dummer, M. Levesque, Y. Koguchi, L. Fong, M. Lotem, M. Baniyash, H. Schmidt, I. M. Svane, G. Kroemer, A. Marabelle, S. Michiels, A. Cavalcanti, M. J. Smyth, J. S. Weber, A. M. Eggermont, L. Zitvogel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/807762e56e0f4dbf9806c82c666da282
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spelling	oai:doaj.org-article:807762e56e0f4dbf9806c82c666da2822021-12-02T14:42:00ZPredictors of responses to immune checkpoint blockade in advanced melanoma10.1038/s41467-017-00608-22041-1723https://doaj.org/article/807762e56e0f4dbf9806c82c666da2822017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00608-2https://doaj.org/toc/2041-1723The clinical management of metastatic melanoma requires predictors of the response to checkpoint blockade. Here, the authors use immunological assays to identify potential prognostic/predictive biomarkers in circulating blood cells and in tumor-infiltrating lymphocytes from patients with resected stage III melanoma.N. JacquelotM. P. RobertiD. P. EnotS. RusakiewiczN. TernèsS. JegouD. M. WoodsA. L. SodréM. HansenY. MeirowM. Sade-FeldmanA. BurraS. S. KwekC. FlamentM. MessaoudeneC. P. M. DuongL. ChenB. S. KwonA. C. AndersonV. K. KuchrooB. WeideF. AubinC. BorgS. DalleO. BeatrixM. AyyoubB. BalmeG. TomasicA. M. Di GiacomoM. MaioD. SchadendorfI. MeleroB. DrénoA. KhammariR. DummerM. LevesqueY. KoguchiL. FongM. LotemM. BaniyashH. SchmidtI. M. SvaneG. KroemerA. MarabelleS. MichielsA. CavalcantiM. J. SmythJ. S. WeberA. M. EggermontL. ZitvogelNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q N. Jacquelot M. P. Roberti D. P. Enot S. Rusakiewicz N. Ternès S. Jegou D. M. Woods A. L. Sodré M. Hansen Y. Meirow M. Sade-Feldman A. Burra S. S. Kwek C. Flament M. Messaoudene C. P. M. Duong L. Chen B. S. Kwon A. C. Anderson V. K. Kuchroo B. Weide F. Aubin C. Borg S. Dalle O. Beatrix M. Ayyoub B. Balme G. Tomasic A. M. Di Giacomo M. Maio D. Schadendorf I. Melero B. Dréno A. Khammari R. Dummer M. Levesque Y. Koguchi L. Fong M. Lotem M. Baniyash H. Schmidt I. M. Svane G. Kroemer A. Marabelle S. Michiels A. Cavalcanti M. J. Smyth J. S. Weber A. M. Eggermont L. Zitvogel Predictors of responses to immune checkpoint blockade in advanced melanoma
description	The clinical management of metastatic melanoma requires predictors of the response to checkpoint blockade. Here, the authors use immunological assays to identify potential prognostic/predictive biomarkers in circulating blood cells and in tumor-infiltrating lymphocytes from patients with resected stage III melanoma.
format	article
author	N. Jacquelot M. P. Roberti D. P. Enot S. Rusakiewicz N. Ternès S. Jegou D. M. Woods A. L. Sodré M. Hansen Y. Meirow M. Sade-Feldman A. Burra S. S. Kwek C. Flament M. Messaoudene C. P. M. Duong L. Chen B. S. Kwon A. C. Anderson V. K. Kuchroo B. Weide F. Aubin C. Borg S. Dalle O. Beatrix M. Ayyoub B. Balme G. Tomasic A. M. Di Giacomo M. Maio D. Schadendorf I. Melero B. Dréno A. Khammari R. Dummer M. Levesque Y. Koguchi L. Fong M. Lotem M. Baniyash H. Schmidt I. M. Svane G. Kroemer A. Marabelle S. Michiels A. Cavalcanti M. J. Smyth J. S. Weber A. M. Eggermont L. Zitvogel
author_facet	N. Jacquelot M. P. Roberti D. P. Enot S. Rusakiewicz N. Ternès S. Jegou D. M. Woods A. L. Sodré M. Hansen Y. Meirow M. Sade-Feldman A. Burra S. S. Kwek C. Flament M. Messaoudene C. P. M. Duong L. Chen B. S. Kwon A. C. Anderson V. K. Kuchroo B. Weide F. Aubin C. Borg S. Dalle O. Beatrix M. Ayyoub B. Balme G. Tomasic A. M. Di Giacomo M. Maio D. Schadendorf I. Melero B. Dréno A. Khammari R. Dummer M. Levesque Y. Koguchi L. Fong M. Lotem M. Baniyash H. Schmidt I. M. Svane G. Kroemer A. Marabelle S. Michiels A. Cavalcanti M. J. Smyth J. S. Weber A. M. Eggermont L. Zitvogel
author_sort	N. Jacquelot
title	Predictors of responses to immune checkpoint blockade in advanced melanoma
title_short	Predictors of responses to immune checkpoint blockade in advanced melanoma
title_full	Predictors of responses to immune checkpoint blockade in advanced melanoma
title_fullStr	Predictors of responses to immune checkpoint blockade in advanced melanoma
title_full_unstemmed	Predictors of responses to immune checkpoint blockade in advanced melanoma
title_sort	predictors of responses to immune checkpoint blockade in advanced melanoma
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/807762e56e0f4dbf9806c82c666da282
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Predictors of responses to immune checkpoint blockade in advanced melanoma

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