Long-term outcomes after endoscopic retrograde pancreatic drainage for symptomatic pancreaticojejunal anastomotic stenosis

Abstract There is limited evidence supporting the usefulness of endoscopic retrograde pancreatic drainage (ERPD) for symptomatic pancreaticojejunal anastomotic stenosis (sPJS). We examined the usefulness of ERPD for sPJS. We conducted a retrospective analysis of 10 benign sPJS patients. A forward-vi...

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Autores principales:	Akihiko Kida, Yukihiro Shirota, Taro Kawane, Hitoshi Omura, Tatsuo Kumai, Masaaki Yano, Fumitaka Arihara, Yuji Hodo, Koichiro Matsuda, Kohei Ogawa, Mitsuru Matsuda, Akito Sakai, Mitsuhiro Terada, Tokio Wakabayashi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/807b0697ce584056b98b0be0bc636728
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spelling	oai:doaj.org-article:807b0697ce584056b98b0be0bc6367282021-12-02T13:35:04ZLong-term outcomes after endoscopic retrograde pancreatic drainage for symptomatic pancreaticojejunal anastomotic stenosis10.1038/s41598-021-84024-z2045-2322https://doaj.org/article/807b0697ce584056b98b0be0bc6367282021-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-84024-zhttps://doaj.org/toc/2045-2322Abstract There is limited evidence supporting the usefulness of endoscopic retrograde pancreatic drainage (ERPD) for symptomatic pancreaticojejunal anastomotic stenosis (sPJS). We examined the usefulness of ERPD for sPJS. We conducted a retrospective analysis of 10 benign sPJS patients. A forward-viewing endoscope was used in all sessions. Following items were evaluated: technical success, adverse events, and clinical outcome of ERPD. The technical success rate was 100% (10/10) in initial ERPD; 9 patients had a pancreatic stent (no-internal-flap: n = 4, internal-flap: n = 5). The median follow-up was 920 days. Four patients developed recurrence. Among them, 3 had a stent with no-internal-flap in initial ERPD, the stent migrated in 3 at recurrence, and a stent was not placed in 1 patient in initial ERPD. Four follow-up interventions were performed. No recurrence was observed in 6 patients. None of the stents migrated (no-internal-flap: n = 1, internal-flap: n = 5) and no stents were replaced due to stent failure. Stenting with no-internal-flap was associated with recurrence (p = 0.042). Mild adverse events developed in 14.3% (2/14). In conclusions, ERPD was performed safely with high technical success. Recurrence was common after stenting with no-internal-flap. Long-term stenting did not result in stent failure. Clinical trial register and their clinical registration number: Nos. 58-115 and R2-9.Akihiko KidaYukihiro ShirotaTaro KawaneHitoshi OmuraTatsuo KumaiMasaaki YanoFumitaka AriharaYuji HodoKoichiro MatsudaKohei OgawaMitsuru MatsudaAkito SakaiMitsuhiro TeradaTokio WakabayashiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Akihiko Kida Yukihiro Shirota Taro Kawane Hitoshi Omura Tatsuo Kumai Masaaki Yano Fumitaka Arihara Yuji Hodo Koichiro Matsuda Kohei Ogawa Mitsuru Matsuda Akito Sakai Mitsuhiro Terada Tokio Wakabayashi Long-term outcomes after endoscopic retrograde pancreatic drainage for symptomatic pancreaticojejunal anastomotic stenosis
description	Abstract There is limited evidence supporting the usefulness of endoscopic retrograde pancreatic drainage (ERPD) for symptomatic pancreaticojejunal anastomotic stenosis (sPJS). We examined the usefulness of ERPD for sPJS. We conducted a retrospective analysis of 10 benign sPJS patients. A forward-viewing endoscope was used in all sessions. Following items were evaluated: technical success, adverse events, and clinical outcome of ERPD. The technical success rate was 100% (10/10) in initial ERPD; 9 patients had a pancreatic stent (no-internal-flap: n = 4, internal-flap: n = 5). The median follow-up was 920 days. Four patients developed recurrence. Among them, 3 had a stent with no-internal-flap in initial ERPD, the stent migrated in 3 at recurrence, and a stent was not placed in 1 patient in initial ERPD. Four follow-up interventions were performed. No recurrence was observed in 6 patients. None of the stents migrated (no-internal-flap: n = 1, internal-flap: n = 5) and no stents were replaced due to stent failure. Stenting with no-internal-flap was associated with recurrence (p = 0.042). Mild adverse events developed in 14.3% (2/14). In conclusions, ERPD was performed safely with high technical success. Recurrence was common after stenting with no-internal-flap. Long-term stenting did not result in stent failure. Clinical trial register and their clinical registration number: Nos. 58-115 and R2-9.
format	article
author	Akihiko Kida Yukihiro Shirota Taro Kawane Hitoshi Omura Tatsuo Kumai Masaaki Yano Fumitaka Arihara Yuji Hodo Koichiro Matsuda Kohei Ogawa Mitsuru Matsuda Akito Sakai Mitsuhiro Terada Tokio Wakabayashi
author_facet	Akihiko Kida Yukihiro Shirota Taro Kawane Hitoshi Omura Tatsuo Kumai Masaaki Yano Fumitaka Arihara Yuji Hodo Koichiro Matsuda Kohei Ogawa Mitsuru Matsuda Akito Sakai Mitsuhiro Terada Tokio Wakabayashi
author_sort	Akihiko Kida
title	Long-term outcomes after endoscopic retrograde pancreatic drainage for symptomatic pancreaticojejunal anastomotic stenosis
title_short	Long-term outcomes after endoscopic retrograde pancreatic drainage for symptomatic pancreaticojejunal anastomotic stenosis
title_full	Long-term outcomes after endoscopic retrograde pancreatic drainage for symptomatic pancreaticojejunal anastomotic stenosis
title_fullStr	Long-term outcomes after endoscopic retrograde pancreatic drainage for symptomatic pancreaticojejunal anastomotic stenosis
title_full_unstemmed	Long-term outcomes after endoscopic retrograde pancreatic drainage for symptomatic pancreaticojejunal anastomotic stenosis
title_sort	long-term outcomes after endoscopic retrograde pancreatic drainage for symptomatic pancreaticojejunal anastomotic stenosis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/807b0697ce584056b98b0be0bc636728
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Long-term outcomes after endoscopic retrograde pancreatic drainage for symptomatic pancreaticojejunal anastomotic stenosis

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