HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism

Narayanan et al. show that local administration of miR-210 accelerates wound healing specifically in diabetic mice. They find that miR-210 restores the metabolic balance in diabetic wounds by activating glycolysis and cellular migration. This study presents miR-210 as a potential therapeutic option...

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Autores principales:	Sampath Narayanan, Sofie Eliasson Angelstig, Cheng Xu, Jacob Grünler, Allan Zhao, Wan Zhu, Ning Xu Landén, Mona Ståhle, Jingping Zhang, Mircea Ivan, Raluca Georgiana Maltesen, Ileana Ruxandra Botusan, Neda Rajamand Ekberg, Xiaowei Zheng, Sergiu-Bogdan Catrina
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/80812abc7eff46a8a33277442fd73105
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spelling	oai:doaj.org-article:80812abc7eff46a8a33277442fd731052021-12-02T13:33:58ZHypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism10.1038/s42003-020-01495-y2399-3642https://doaj.org/article/80812abc7eff46a8a33277442fd731052020-12-01T00:00:00Zhttps://doi.org/10.1038/s42003-020-01495-yhttps://doaj.org/toc/2399-3642Narayanan et al. show that local administration of miR-210 accelerates wound healing specifically in diabetic mice. They find that miR-210 restores the metabolic balance in diabetic wounds by activating glycolysis and cellular migration. This study presents miR-210 as a potential therapeutic option to treat diabetic wound healing.Sampath NarayananSofie Eliasson AngelstigCheng XuJacob GrünlerAllan ZhaoWan ZhuNing Xu LandénMona StåhleJingping ZhangMircea IvanRaluca Georgiana MaltesenIleana Ruxandra BotusanNeda Rajamand EkbergXiaowei ZhengSergiu-Bogdan CatrinaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 3, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Sampath Narayanan Sofie Eliasson Angelstig Cheng Xu Jacob Grünler Allan Zhao Wan Zhu Ning Xu Landén Mona Ståhle Jingping Zhang Mircea Ivan Raluca Georgiana Maltesen Ileana Ruxandra Botusan Neda Rajamand Ekberg Xiaowei Zheng Sergiu-Bogdan Catrina HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism
description	Narayanan et al. show that local administration of miR-210 accelerates wound healing specifically in diabetic mice. They find that miR-210 restores the metabolic balance in diabetic wounds by activating glycolysis and cellular migration. This study presents miR-210 as a potential therapeutic option to treat diabetic wound healing.
format	article
author	Sampath Narayanan Sofie Eliasson Angelstig Cheng Xu Jacob Grünler Allan Zhao Wan Zhu Ning Xu Landén Mona Ståhle Jingping Zhang Mircea Ivan Raluca Georgiana Maltesen Ileana Ruxandra Botusan Neda Rajamand Ekberg Xiaowei Zheng Sergiu-Bogdan Catrina
author_facet	Sampath Narayanan Sofie Eliasson Angelstig Cheng Xu Jacob Grünler Allan Zhao Wan Zhu Ning Xu Landén Mona Ståhle Jingping Zhang Mircea Ivan Raluca Georgiana Maltesen Ileana Ruxandra Botusan Neda Rajamand Ekberg Xiaowei Zheng Sergiu-Bogdan Catrina
author_sort	Sampath Narayanan
title	HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism
title_short	HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism
title_full	HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism
title_fullStr	HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism
title_full_unstemmed	HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism
title_sort	hypoxamir-210 accelerates wound healing in diabetic mice by improving cellular metabolism
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/80812abc7eff46a8a33277442fd73105
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HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism

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