MUC1 limits Helicobacter pylori infection both by steric hindrance and by acting as a releasable decoy.
The bacterium Helicobacter pylori can cause peptic ulcer disease, gastric adenocarcinoma and MALT lymphoma. The cell-surface mucin MUC1 is a large glycoprotein which is highly expressed on the mucosal surface and limits the density of H. pylori in a murine infection model. We now demonstrate that by...
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| Auteurs principaux: | , , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2009
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/8088459c1b2e435baa2308dee51d9eab |
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