Differential diagnoses and management strategies in patients with schizophrenia and bipolar disorder

A Carlo Altamura1, Jose M Goikolea21Department of Psychiatry, University of Milan, IRCCS Fondazione Ospedale Maggiore Policlinico Mangiagalli e Regina Elena, Milan, Italy; 2Bipolar Disorder Program, Hospital Clinic i Universitari, Barcelona, SpainAbstract: Successful treatment of psychiatric disorde...

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Autores principales:	A Carlo Altamura, Jose M Goikolea
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2008
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/80903c46c2964a0ca5654283910af3f2
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spelling	oai:doaj.org-article:80903c46c2964a0ca5654283910af3f22021-12-02T01:02:33ZDifferential diagnoses and management strategies in patients with schizophrenia and bipolar disorder1176-63281178-2021https://doaj.org/article/80903c46c2964a0ca5654283910af3f22008-03-01T00:00:00Zhttp://www.dovepress.com/differential-diagnoses-and-management-strategies-in-patients-with-schi-a1015https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021A Carlo Altamura1, Jose M Goikolea21Department of Psychiatry, University of Milan, IRCCS Fondazione Ospedale Maggiore Policlinico Mangiagalli e Regina Elena, Milan, Italy; 2Bipolar Disorder Program, Hospital Clinic i Universitari, Barcelona, SpainAbstract: Successful treatment of psychiatric disorders, including bipolar disorder and schizophrenia, is complicated and is affected by a broad range of factors associated with the diagnosis, choice of treatment and social factors. In these patients, treatment management must focus on accurate and early diagnosis, to ensure that correct treatment is administered as soon as possible. In both disorders, the treatment of the disease in the acute phase must be maintained long term to provide continuous relief and normal function; the treatment choice in the early stages of the disease may impact on long-term outcomes. In schizophrenia, treatment non-compliance is an important issue, with up to 50% of patients discontinuing treatment for reasons as diverse as efficacy failure, social barriers, and more commonly, adverse events. Treatment non-compliance also remains an issue in bipolar disorder, as tolerability of mood stabilizers, especially lithium, is not always good, and combination treatments are frequent. In order to achieve an optimal outcome in which the patient continues with their medication lifelong, treatment should be tailored to each individual, taking into account treatment and family history, and balancing efficacy with tolerability to maximize patient benefit and minimize the risk of discontinuation. These case studies illustrate how treatment should be monitored, tailored and often changed over time to meet these needs.Keywords: bipolar disorder, recurrence, treatment management, schizophrenia, non-compliance, adverse events A Carlo AltamuraJose M GoikoleaDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2008, Iss Issue 1, Pp 311-317 (2008)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 A Carlo Altamura Jose M Goikolea Differential diagnoses and management strategies in patients with schizophrenia and bipolar disorder
description	A Carlo Altamura1, Jose M Goikolea21Department of Psychiatry, University of Milan, IRCCS Fondazione Ospedale Maggiore Policlinico Mangiagalli e Regina Elena, Milan, Italy; 2Bipolar Disorder Program, Hospital Clinic i Universitari, Barcelona, SpainAbstract: Successful treatment of psychiatric disorders, including bipolar disorder and schizophrenia, is complicated and is affected by a broad range of factors associated with the diagnosis, choice of treatment and social factors. In these patients, treatment management must focus on accurate and early diagnosis, to ensure that correct treatment is administered as soon as possible. In both disorders, the treatment of the disease in the acute phase must be maintained long term to provide continuous relief and normal function; the treatment choice in the early stages of the disease may impact on long-term outcomes. In schizophrenia, treatment non-compliance is an important issue, with up to 50% of patients discontinuing treatment for reasons as diverse as efficacy failure, social barriers, and more commonly, adverse events. Treatment non-compliance also remains an issue in bipolar disorder, as tolerability of mood stabilizers, especially lithium, is not always good, and combination treatments are frequent. In order to achieve an optimal outcome in which the patient continues with their medication lifelong, treatment should be tailored to each individual, taking into account treatment and family history, and balancing efficacy with tolerability to maximize patient benefit and minimize the risk of discontinuation. These case studies illustrate how treatment should be monitored, tailored and often changed over time to meet these needs.Keywords: bipolar disorder, recurrence, treatment management, schizophrenia, non-compliance, adverse events
format	article
author	A Carlo Altamura Jose M Goikolea
author_facet	A Carlo Altamura Jose M Goikolea
author_sort	A Carlo Altamura
title	Differential diagnoses and management strategies in patients with schizophrenia and bipolar disorder
title_short	Differential diagnoses and management strategies in patients with schizophrenia and bipolar disorder
title_full	Differential diagnoses and management strategies in patients with schizophrenia and bipolar disorder
title_fullStr	Differential diagnoses and management strategies in patients with schizophrenia and bipolar disorder
title_full_unstemmed	Differential diagnoses and management strategies in patients with schizophrenia and bipolar disorder
title_sort	differential diagnoses and management strategies in patients with schizophrenia and bipolar disorder
publisher	Dove Medical Press
publishDate	2008
url	https://doaj.org/article/80903c46c2964a0ca5654283910af3f2
work_keys_str_mv	AT acarloaltamura differentialdiagnosesandmanagementstrategiesinpatientswithschizophreniaandbipolardisorder AT josemgoikolea differentialdiagnosesandmanagementstrategiesinpatientswithschizophreniaandbipolardisorder
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Differential diagnoses and management strategies in patients with schizophrenia and bipolar disorder

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