Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3

In most mammals, imprinted genes contain epigenetic marks that differ in each parental genome and control their parent-of-origin-specific expression. Here, the authors map imprinted genes in mouse preimplantation embryos and find that imprinted gene expression in blastocysts is mainly dependent on P...

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Autores principales:	Laura Santini, Florian Halbritter, Fabian Titz-Teixeira, Toru Suzuki, Maki Asami, Xiaoyan Ma, Julia Ramesmayer, Andreas Lackner, Nick Warr, Florian Pauler, Simon Hippenmeyer, Ernest Laue, Matthias Farlik, Christoph Bock, Andreas Beyer, Anthony C. F. Perry, Martin Leeb
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/80a4a9c1e8f242dab49a92d2bed3b3ac
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spelling	oai:doaj.org-article:80a4a9c1e8f242dab49a92d2bed3b3ac2021-12-02T17:45:09ZGenomic imprinting in mouse blastocysts is predominantly associated with H3K27me310.1038/s41467-021-23510-42041-1723https://doaj.org/article/80a4a9c1e8f242dab49a92d2bed3b3ac2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23510-4https://doaj.org/toc/2041-1723In most mammals, imprinted genes contain epigenetic marks that differ in each parental genome and control their parent-of-origin-specific expression. Here, the authors map imprinted genes in mouse preimplantation embryos and find that imprinted gene expression in blastocysts is mainly dependent on Polycomb-mediated H3K27me3-associated gene silencing.Laura SantiniFlorian HalbritterFabian Titz-TeixeiraToru SuzukiMaki AsamiXiaoyan MaJulia RamesmayerAndreas LacknerNick WarrFlorian PaulerSimon HippenmeyerErnest LaueMatthias FarlikChristoph BockAndreas BeyerAnthony C. F. PerryMartin LeebNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Laura Santini Florian Halbritter Fabian Titz-Teixeira Toru Suzuki Maki Asami Xiaoyan Ma Julia Ramesmayer Andreas Lackner Nick Warr Florian Pauler Simon Hippenmeyer Ernest Laue Matthias Farlik Christoph Bock Andreas Beyer Anthony C. F. Perry Martin Leeb Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3
description	In most mammals, imprinted genes contain epigenetic marks that differ in each parental genome and control their parent-of-origin-specific expression. Here, the authors map imprinted genes in mouse preimplantation embryos and find that imprinted gene expression in blastocysts is mainly dependent on Polycomb-mediated H3K27me3-associated gene silencing.
format	article
author	Laura Santini Florian Halbritter Fabian Titz-Teixeira Toru Suzuki Maki Asami Xiaoyan Ma Julia Ramesmayer Andreas Lackner Nick Warr Florian Pauler Simon Hippenmeyer Ernest Laue Matthias Farlik Christoph Bock Andreas Beyer Anthony C. F. Perry Martin Leeb
author_facet	Laura Santini Florian Halbritter Fabian Titz-Teixeira Toru Suzuki Maki Asami Xiaoyan Ma Julia Ramesmayer Andreas Lackner Nick Warr Florian Pauler Simon Hippenmeyer Ernest Laue Matthias Farlik Christoph Bock Andreas Beyer Anthony C. F. Perry Martin Leeb
author_sort	Laura Santini
title	Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3
title_short	Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3
title_full	Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3
title_fullStr	Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3
title_full_unstemmed	Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3
title_sort	genomic imprinting in mouse blastocysts is predominantly associated with h3k27me3
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/80a4a9c1e8f242dab49a92d2bed3b3ac
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Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3

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