Cellular uptake and antitumor activity of DOX-hyd-PEG-FA nanoparticles.

Cellular uptake and antitumor activity of DOX-hyd-PEG-FA nanoparticles.

A PEG-based, folate mediated, active tumor targeting drug delivery system using DOX-hyd-PEG-FA nanoparticles (NPs) were prepared. DOX-hyd-PEG-FA NPs showed a significantly faster DOX release in pH 5.0 medium than in pH 7.4 medium. Compared with DOX-hyd-PEG NPs, DOX-hyd-PEG-FA NPs increased the intra...

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Autores principales: Wei-liang Ye, Jiang-bo Du, Bang-le Zhang, Ren Na, Yan-feng Song, Qi-bing Mei, Ming-gao Zhao, Si-yuan Zhou
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/80a4eb0980d54e93a5c8da5ddaa2dfef
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