Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos

In animal embryos, maternally deposited mRNAs are degraded by several different mechanisms. Here the authors show that C. elegans embryos inherit antisense pool of small RNAs which are loaded into CSR-1 and cleave complementary maternal mRNAs.

Saved in:
Bibliographic Details
Main Authors: Piergiuseppe Quarato, Meetali Singh, Eric Cornes, Blaise Li, Loan Bourdon, Florian Mueller, Celine Didier, Germano Cecere
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Q
Online Access:https://doaj.org/article/80a5b97e138c4ff592d59e5356b36c83
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In animal embryos, maternally deposited mRNAs are degraded by several different mechanisms. Here the authors show that C. elegans embryos inherit antisense pool of small RNAs which are loaded into CSR-1 and cleave complementary maternal mRNAs.