Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos
In animal embryos, maternally deposited mRNAs are degraded by several different mechanisms. Here the authors show that C. elegans embryos inherit antisense pool of small RNAs which are loaded into CSR-1 and cleave complementary maternal mRNAs.
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Nature Portfolio
2021
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oai:doaj.org-article:80a5b97e138c4ff592d59e5356b36c832021-12-02T15:52:37ZGermline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos10.1038/s41467-021-21691-62041-1723https://doaj.org/article/80a5b97e138c4ff592d59e5356b36c832021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21691-6https://doaj.org/toc/2041-1723In animal embryos, maternally deposited mRNAs are degraded by several different mechanisms. Here the authors show that C. elegans embryos inherit antisense pool of small RNAs which are loaded into CSR-1 and cleave complementary maternal mRNAs.Piergiuseppe QuaratoMeetali SinghEric CornesBlaise LiLoan BourdonFlorian MuellerCeline DidierGermano CecereNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
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Science Q |
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Science Q Piergiuseppe Quarato Meetali Singh Eric Cornes Blaise Li Loan Bourdon Florian Mueller Celine Didier Germano Cecere Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos |
description |
In animal embryos, maternally deposited mRNAs are degraded by several different mechanisms. Here the authors show that C. elegans embryos inherit antisense pool of small RNAs which are loaded into CSR-1 and cleave complementary maternal mRNAs. |
format |
article |
author |
Piergiuseppe Quarato Meetali Singh Eric Cornes Blaise Li Loan Bourdon Florian Mueller Celine Didier Germano Cecere |
author_facet |
Piergiuseppe Quarato Meetali Singh Eric Cornes Blaise Li Loan Bourdon Florian Mueller Celine Didier Germano Cecere |
author_sort |
Piergiuseppe Quarato |
title |
Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos |
title_short |
Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos |
title_full |
Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos |
title_fullStr |
Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos |
title_full_unstemmed |
Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos |
title_sort |
germline inherited small rnas facilitate the clearance of untranslated maternal mrnas in c. elegans embryos |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/80a5b97e138c4ff592d59e5356b36c83 |
work_keys_str_mv |
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1718385581854031872 |