Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos

In animal embryos, maternally deposited mRNAs are degraded by several different mechanisms. Here the authors show that C. elegans embryos inherit antisense pool of small RNAs which are loaded into CSR-1 and cleave complementary maternal mRNAs.

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Auteurs principaux: Piergiuseppe Quarato, Meetali Singh, Eric Cornes, Blaise Li, Loan Bourdon, Florian Mueller, Celine Didier, Germano Cecere
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/80a5b97e138c4ff592d59e5356b36c83
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spelling oai:doaj.org-article:80a5b97e138c4ff592d59e5356b36c832021-12-02T15:52:37ZGermline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos10.1038/s41467-021-21691-62041-1723https://doaj.org/article/80a5b97e138c4ff592d59e5356b36c832021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21691-6https://doaj.org/toc/2041-1723In animal embryos, maternally deposited mRNAs are degraded by several different mechanisms. Here the authors show that C. elegans embryos inherit antisense pool of small RNAs which are loaded into CSR-1 and cleave complementary maternal mRNAs.Piergiuseppe QuaratoMeetali SinghEric CornesBlaise LiLoan BourdonFlorian MuellerCeline DidierGermano CecereNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Piergiuseppe Quarato
Meetali Singh
Eric Cornes
Blaise Li
Loan Bourdon
Florian Mueller
Celine Didier
Germano Cecere
Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos
description In animal embryos, maternally deposited mRNAs are degraded by several different mechanisms. Here the authors show that C. elegans embryos inherit antisense pool of small RNAs which are loaded into CSR-1 and cleave complementary maternal mRNAs.
format article
author Piergiuseppe Quarato
Meetali Singh
Eric Cornes
Blaise Li
Loan Bourdon
Florian Mueller
Celine Didier
Germano Cecere
author_facet Piergiuseppe Quarato
Meetali Singh
Eric Cornes
Blaise Li
Loan Bourdon
Florian Mueller
Celine Didier
Germano Cecere
author_sort Piergiuseppe Quarato
title Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos
title_short Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos
title_full Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos
title_fullStr Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos
title_full_unstemmed Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos
title_sort germline inherited small rnas facilitate the clearance of untranslated maternal mrnas in c. elegans embryos
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/80a5b97e138c4ff592d59e5356b36c83
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