Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer
In prostate cancer tumour aggressiveness can be related to race. Here, the authors identify an alternative RNA splice variant of PIK3CD as a potential mechanism to explain racial disparities in the incidence and aggressiveness of prostate cancer between African American and European American men.
Guardado en:
Autores principales: | Bi-Dar Wang, Kristin Ceniccola, SuJin Hwang, Ramez Andrawis, Anelia Horvath, Jennifer A. Freedman, Jacqueline Olender, Stefan Knapp, Travers Ching, Lana Garmire, Vyomesh Patel, Mariano A. Garcia-Blanco, Steven R. Patierno, Norman H. Lee |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/80c476f7db414f898da67a1d441f9eec |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Correction: Corrigendum: Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer
por: Bi-Dar Wang, et al.
Publicado: (2017) -
Using single nucleotide variations in single-cell RNA-seq to identify subpopulations and genotype-phenotype linkage
por: Olivier Poirion, et al.
Publicado: (2018) -
Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness
por: Alexandra Avgustinova, et al.
Publicado: (2016) -
Modelling the microenvironment of the most aggressive brain tumours for preclinical studies
por: Juš Žavbi, et al.
Publicado: (2021) -
Identification of tumour immune microenvironment-related alternative splicing events for the prognostication of pancreatic adenocarcinoma
por: Bo Chen, et al.
Publicado: (2021)