Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy
Recent studies have proposed that intracellular water is different from bulk water at the molecular level. Here the authors introduce a Raman microscopy-based method to image the distribution of water states in living cells, and report intracellular water heterogeneity between nucleus and cytoplasm....
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2019
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oai:doaj.org-article:80cf5a5763e74dca843764790eb9fa802021-12-02T16:57:23ZOptical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy10.1038/s41467-019-12708-22041-1723https://doaj.org/article/80cf5a5763e74dca843764790eb9fa802019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12708-2https://doaj.org/toc/2041-1723Recent studies have proposed that intracellular water is different from bulk water at the molecular level. Here the authors introduce a Raman microscopy-based method to image the distribution of water states in living cells, and report intracellular water heterogeneity between nucleus and cytoplasm.Lixue ShiFanghao HuWei MinNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-8 (2019) |
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Science Q Lixue Shi Fanghao Hu Wei Min Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy |
description |
Recent studies have proposed that intracellular water is different from bulk water at the molecular level. Here the authors introduce a Raman microscopy-based method to image the distribution of water states in living cells, and report intracellular water heterogeneity between nucleus and cytoplasm. |
format |
article |
author |
Lixue Shi Fanghao Hu Wei Min |
author_facet |
Lixue Shi Fanghao Hu Wei Min |
author_sort |
Lixue Shi |
title |
Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy |
title_short |
Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy |
title_full |
Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy |
title_fullStr |
Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy |
title_full_unstemmed |
Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy |
title_sort |
optical mapping of biological water in single live cells by stimulated raman excited fluorescence microscopy |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/80cf5a5763e74dca843764790eb9fa80 |
work_keys_str_mv |
AT lixueshi opticalmappingofbiologicalwaterinsinglelivecellsbystimulatedramanexcitedfluorescencemicroscopy AT fanghaohu opticalmappingofbiologicalwaterinsinglelivecellsbystimulatedramanexcitedfluorescencemicroscopy AT weimin opticalmappingofbiologicalwaterinsinglelivecellsbystimulatedramanexcitedfluorescencemicroscopy |
_version_ |
1718382575495413760 |