Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy

Recent studies have proposed that intracellular water is different from bulk water at the molecular level. Here the authors introduce a Raman microscopy-based method to image the distribution of water states in living cells, and report intracellular water heterogeneity between nucleus and cytoplasm....

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Main Authors: Lixue Shi, Fanghao Hu, Wei Min
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/80cf5a5763e74dca843764790eb9fa80
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spelling oai:doaj.org-article:80cf5a5763e74dca843764790eb9fa802021-12-02T16:57:23ZOptical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy10.1038/s41467-019-12708-22041-1723https://doaj.org/article/80cf5a5763e74dca843764790eb9fa802019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12708-2https://doaj.org/toc/2041-1723Recent studies have proposed that intracellular water is different from bulk water at the molecular level. Here the authors introduce a Raman microscopy-based method to image the distribution of water states in living cells, and report intracellular water heterogeneity between nucleus and cytoplasm.Lixue ShiFanghao HuWei MinNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lixue Shi
Fanghao Hu
Wei Min
Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy
description Recent studies have proposed that intracellular water is different from bulk water at the molecular level. Here the authors introduce a Raman microscopy-based method to image the distribution of water states in living cells, and report intracellular water heterogeneity between nucleus and cytoplasm.
format article
author Lixue Shi
Fanghao Hu
Wei Min
author_facet Lixue Shi
Fanghao Hu
Wei Min
author_sort Lixue Shi
title Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy
title_short Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy
title_full Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy
title_fullStr Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy
title_full_unstemmed Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy
title_sort optical mapping of biological water in single live cells by stimulated raman excited fluorescence microscopy
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/80cf5a5763e74dca843764790eb9fa80
work_keys_str_mv AT lixueshi opticalmappingofbiologicalwaterinsinglelivecellsbystimulatedramanexcitedfluorescencemicroscopy
AT fanghaohu opticalmappingofbiologicalwaterinsinglelivecellsbystimulatedramanexcitedfluorescencemicroscopy
AT weimin opticalmappingofbiologicalwaterinsinglelivecellsbystimulatedramanexcitedfluorescencemicroscopy
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