Silent presentation of B-Cell Lymphoma in the mandible

The manifestation of extranodal non-Hodgkin lymphoma in the mandible is uncommon. Classically, presence of swelling, teeth mobility, pain and paraesthesia intraorally are pathognomonic signs of oral malignancies. However, there are very few reported cases of oral manifestation of lymphoma with the o...

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Autores principales:	H. Javed, C.Y. Chieng, S. Paraneetharan
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2022
Materias:	Lymphoma Non-hodgkins lymphoma B-Cell lymphoma Numb chin syndrome NCS Mandible Internal medicine RC31-1245 Surgery RD1-811
Acceso en línea:	https://doaj.org/article/80d5a9878058421f9c14f9a6f8bc1300
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spelling	oai:doaj.org-article:80d5a9878058421f9c14f9a6f8bc13002021-11-10T04:44:01ZSilent presentation of B-Cell Lymphoma in the mandible2667-147610.1016/j.adoms.2021.100210https://doaj.org/article/80d5a9878058421f9c14f9a6f8bc13002022-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2667147621001990https://doaj.org/toc/2667-1476The manifestation of extranodal non-Hodgkin lymphoma in the mandible is uncommon. Classically, presence of swelling, teeth mobility, pain and paraesthesia intraorally are pathognomonic signs of oral malignancies. However, there are very few reported cases of oral manifestation of lymphoma with the only complaint being numb chin syndrome. Here, we report a 50-year-old patient who presented with numb chin syndrome and no clinical evidence of malignancy intraorally. Further investigations and biopsy confirmed the presence of diffuse B-cell lymphoma. This case highlights the diagnostic challenges of silent presentation of B-cell lymphoma in the mandible. Furthermore, numb chin syndrome can be an early presentation of oral malignancy and hence, clinicians should have a low threshold for urgent referral to secondary care and for thorough investigation to avoid misdiagnosis and treatment delays.H. JavedC.Y. ChiengS. ParaneetharanElsevierarticleLymphomaNon-hodgkins lymphomaB-Cell lymphomaNumb chin syndromeNCSMandibleInternal medicineRC31-1245SurgeryRD1-811ENAdvances in Oral and Maxillofacial Surgery, Vol 5, Iss , Pp 100210- (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	Lymphoma Non-hodgkins lymphoma B-Cell lymphoma Numb chin syndrome NCS Mandible Internal medicine RC31-1245 Surgery RD1-811
spellingShingle	Lymphoma Non-hodgkins lymphoma B-Cell lymphoma Numb chin syndrome NCS Mandible Internal medicine RC31-1245 Surgery RD1-811 H. Javed C.Y. Chieng S. Paraneetharan Silent presentation of B-Cell Lymphoma in the mandible
description	The manifestation of extranodal non-Hodgkin lymphoma in the mandible is uncommon. Classically, presence of swelling, teeth mobility, pain and paraesthesia intraorally are pathognomonic signs of oral malignancies. However, there are very few reported cases of oral manifestation of lymphoma with the only complaint being numb chin syndrome. Here, we report a 50-year-old patient who presented with numb chin syndrome and no clinical evidence of malignancy intraorally. Further investigations and biopsy confirmed the presence of diffuse B-cell lymphoma. This case highlights the diagnostic challenges of silent presentation of B-cell lymphoma in the mandible. Furthermore, numb chin syndrome can be an early presentation of oral malignancy and hence, clinicians should have a low threshold for urgent referral to secondary care and for thorough investigation to avoid misdiagnosis and treatment delays.
format	article
author	H. Javed C.Y. Chieng S. Paraneetharan
author_facet	H. Javed C.Y. Chieng S. Paraneetharan
author_sort	H. Javed
title	Silent presentation of B-Cell Lymphoma in the mandible
title_short	Silent presentation of B-Cell Lymphoma in the mandible
title_full	Silent presentation of B-Cell Lymphoma in the mandible
title_fullStr	Silent presentation of B-Cell Lymphoma in the mandible
title_full_unstemmed	Silent presentation of B-Cell Lymphoma in the mandible
title_sort	silent presentation of b-cell lymphoma in the mandible
publisher	Elsevier
publishDate	2022
url	https://doaj.org/article/80d5a9878058421f9c14f9a6f8bc1300
work_keys_str_mv	AT hjaved silentpresentationofbcelllymphomainthemandible AT cychieng silentpresentationofbcelllymphomainthemandible AT sparaneetharan silentpresentationofbcelllymphomainthemandible
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Silent presentation of B-Cell Lymphoma in the mandible

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