IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA
Abstract. Sixteen children from 3 to 6 years old with complicated premorbid background, carrying S. pneumoniae, who had inflammation markers (altered IL-6 and TNFα amounts in peripheral blood analysis)тalong with immunological deficiency, were vaccinated with a «Pneumo 23» preparation. A good tolera...
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| Auteurs principaux: | , , , , |
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| Format: | article |
| Langue: | RU |
| Publié: |
SPb RAACI
2014
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/80e0c0a4726548f188fe39c6192fb51e |
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| Résumé: | Abstract. Sixteen children from 3 to 6 years old with complicated premorbid background, carrying S. pneumoniae, who had inflammation markers (altered IL-6 and TNFα amounts in peripheral blood analysis)тalong with immunological deficiency, were vaccinated with a «Pneumo 23» preparation. A good tolerance of «Pneumo 23» vaccine was determined. A significant increase of specific antibodies was established both to pneumococcal polysaccharides and to polysaccharides, containing in «Pneumo 23». A tendency to diminished inflammatory events and activated immunological response was revealed, that was expressed as a decrease of serum IL-6 and increase in TNFα. |
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