IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA
Abstract. Sixteen children from 3 to 6 years old with complicated premorbid background, carrying S. pneumoniae, who had inflammation markers (altered IL-6 and TNFα amounts in peripheral blood analysis)тalong with immunological deficiency, were vaccinated with a «Pneumo 23» preparation. A good tolera...
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2014
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oai:doaj.org-article:80e0c0a4726548f188fe39c6192fb51e2021-11-18T08:03:40ZIMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA1563-06252313-741X10.15789/1563-0625-2009-2-3-289-292https://doaj.org/article/80e0c0a4726548f188fe39c6192fb51e2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/326https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Sixteen children from 3 to 6 years old with complicated premorbid background, carrying S. pneumoniae, who had inflammation markers (altered IL-6 and TNFα amounts in peripheral blood analysis)тalong with immunological deficiency, were vaccinated with a «Pneumo 23» preparation. A good tolerance of «Pneumo 23» vaccine was determined. A significant increase of specific antibodies was established both to pneumococcal polysaccharides and to polysaccharides, containing in «Pneumo 23». A tendency to diminished inflammatory events and activated immunological response was revealed, that was expressed as a decrease of serum IL-6 and increase in TNFα.A. L. SizonenkoS. N. BeniovaM. P. KostinovE. V. MarkelovaS. V. TaranovaSPb RAACIarticlepneumococci infectionbacteriocarrierimmunitypneumo 23Immunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 11, Iss 2-3, Pp 289-292 (2014) |
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DOAJ |
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topic |
pneumococci infection bacteriocarrier immunity pneumo 23 Immunologic diseases. Allergy RC581-607 |
spellingShingle |
pneumococci infection bacteriocarrier immunity pneumo 23 Immunologic diseases. Allergy RC581-607 A. L. Sizonenko S. N. Beniova M. P. Kostinov E. V. Markelova S. V. Taranova IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA |
description |
Abstract. Sixteen children from 3 to 6 years old with complicated premorbid background, carrying S. pneumoniae, who had inflammation markers (altered IL-6 and TNFα amounts in peripheral blood analysis)тalong with immunological deficiency, were vaccinated with a «Pneumo 23» preparation. A good tolerance of «Pneumo 23» vaccine was determined. A significant increase of specific antibodies was established both to pneumococcal polysaccharides and to polysaccharides, containing in «Pneumo 23». A tendency to diminished inflammatory events and activated immunological response was revealed, that was expressed as a decrease of serum IL-6 and increase in TNFα. |
format |
article |
author |
A. L. Sizonenko S. N. Beniova M. P. Kostinov E. V. Markelova S. V. Taranova |
author_facet |
A. L. Sizonenko S. N. Beniova M. P. Kostinov E. V. Markelova S. V. Taranova |
author_sort |
A. L. Sizonenko |
title |
IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA |
title_short |
IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA |
title_full |
IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA |
title_fullStr |
IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA |
title_full_unstemmed |
IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA |
title_sort |
immunological effect produced by vaccination with «pneumo 23» of children with carriage of streptococcus pneumonia |
publisher |
SPb RAACI |
publishDate |
2014 |
url |
https://doaj.org/article/80e0c0a4726548f188fe39c6192fb51e |
work_keys_str_mv |
AT alsizonenko immunologicaleffectproducedbyvaccinationwithpneumo23ofchildrenwithcarriageofstreptococcuspneumonia AT snbeniova immunologicaleffectproducedbyvaccinationwithpneumo23ofchildrenwithcarriageofstreptococcuspneumonia AT mpkostinov immunologicaleffectproducedbyvaccinationwithpneumo23ofchildrenwithcarriageofstreptococcuspneumonia AT evmarkelova immunologicaleffectproducedbyvaccinationwithpneumo23ofchildrenwithcarriageofstreptococcuspneumonia AT svtaranova immunologicaleffectproducedbyvaccinationwithpneumo23ofchildrenwithcarriageofstreptococcuspneumonia |
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