IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA

Abstract. Sixteen children from 3 to 6 years old with complicated premorbid background, carrying S. pneumoniae, who had inflammation markers (altered IL-6 and TNFα amounts in peripheral blood analysis)тalong with immunological deficiency, were vaccinated with a «Pneumo 23» preparation. A good tolera...

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Autores principales: A. L. Sizonenko, S. N. Beniova, M. P. Kostinov, E. V. Markelova, S. V. Taranova
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Lenguaje:RU
Publicado: SPb RAACI 2014
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Acceso en línea:https://doaj.org/article/80e0c0a4726548f188fe39c6192fb51e
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spelling oai:doaj.org-article:80e0c0a4726548f188fe39c6192fb51e2021-11-18T08:03:40ZIMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA1563-06252313-741X10.15789/1563-0625-2009-2-3-289-292https://doaj.org/article/80e0c0a4726548f188fe39c6192fb51e2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/326https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Sixteen children from 3 to 6 years old with complicated premorbid background, carrying S. pneumoniae, who had inflammation markers (altered IL-6 and TNFα amounts in peripheral blood analysis)тalong with immunological deficiency, were vaccinated with a «Pneumo 23» preparation. A good tolerance of «Pneumo 23» vaccine was determined. A significant increase of specific antibodies was established both to pneumococcal polysaccharides and to polysaccharides, containing in «Pneumo 23». A tendency to diminished inflammatory events and activated immunological response was revealed, that was expressed as a decrease of serum IL-6 and increase in TNFα.A. L. SizonenkoS. N. BeniovaM. P. KostinovE. V. MarkelovaS. V. TaranovaSPb RAACIarticlepneumococci infectionbacteriocarrierimmunitypneumo 23Immunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 11, Iss 2-3, Pp 289-292 (2014)
institution DOAJ
collection DOAJ
language RU
topic pneumococci infection
bacteriocarrier
immunity
pneumo 23
Immunologic diseases. Allergy
RC581-607
spellingShingle pneumococci infection
bacteriocarrier
immunity
pneumo 23
Immunologic diseases. Allergy
RC581-607
A. L. Sizonenko
S. N. Beniova
M. P. Kostinov
E. V. Markelova
S. V. Taranova
IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA
description Abstract. Sixteen children from 3 to 6 years old with complicated premorbid background, carrying S. pneumoniae, who had inflammation markers (altered IL-6 and TNFα amounts in peripheral blood analysis)тalong with immunological deficiency, were vaccinated with a «Pneumo 23» preparation. A good tolerance of «Pneumo 23» vaccine was determined. A significant increase of specific antibodies was established both to pneumococcal polysaccharides and to polysaccharides, containing in «Pneumo 23». A tendency to diminished inflammatory events and activated immunological response was revealed, that was expressed as a decrease of serum IL-6 and increase in TNFα.
format article
author A. L. Sizonenko
S. N. Beniova
M. P. Kostinov
E. V. Markelova
S. V. Taranova
author_facet A. L. Sizonenko
S. N. Beniova
M. P. Kostinov
E. V. Markelova
S. V. Taranova
author_sort A. L. Sizonenko
title IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA
title_short IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA
title_full IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA
title_fullStr IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA
title_full_unstemmed IMMUNOLOGICAL EFFECT PRODUCED BY VACCINATION WITH «PNEUMO 23» OF CHILDREN WITH CARRIAGE OF STREPTOCOCCUS PNEUMONIA
title_sort immunological effect produced by vaccination with «pneumo 23» of children with carriage of streptococcus pneumonia
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/80e0c0a4726548f188fe39c6192fb51e
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AT evmarkelova immunologicaleffectproducedbyvaccinationwithpneumo23ofchildrenwithcarriageofstreptococcuspneumonia
AT svtaranova immunologicaleffectproducedbyvaccinationwithpneumo23ofchildrenwithcarriageofstreptococcuspneumonia
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