Surveillance of antibiotic sensitivity pattern in chronic suppurative otitis media of an Indian teaching hospital

Introduction: Chronic suppurative otitis media (CSOM) is a common problem in worldwide and untreated CSOM leads to fatal complications like facial nerve paralysis, lateral sinus thrombosis, labyrinthitis, meningitis and brain abscess in developing country like India. Objective: To isolate causative...

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Autores principales:	Mahesh Chandra Sahu, Santosh Kumar Swain
Formato:	article
Lenguaje:	EN
Publicado:	KeAi Communications Co., Ltd. 2019
Materias:	Otorhinolaryngology RF1-547 Surgery RD1-811
Acceso en línea:	https://doaj.org/article/80e2c4f51dea46dea00e9ccd1e90759e
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spelling	oai:doaj.org-article:80e2c4f51dea46dea00e9ccd1e90759e2021-12-02T12:52:22ZSurveillance of antibiotic sensitivity pattern in chronic suppurative otitis media of an Indian teaching hospital2095-881110.1016/j.wjorl.2018.05.008https://doaj.org/article/80e2c4f51dea46dea00e9ccd1e90759e2019-06-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095881118300076https://doaj.org/toc/2095-8811Introduction: Chronic suppurative otitis media (CSOM) is a common problem in worldwide and untreated CSOM leads to fatal complications like facial nerve paralysis, lateral sinus thrombosis, labyrinthitis, meningitis and brain abscess in developing country like India. Objective: To isolate causative bacteria and antibiotic sensitivity pattern for CSOM and to know the prevalence of extended spectrum beta lactamases (ESBL) and Metallobetalactamases (MBL) in CSOM patients. Methods: A total of 500 ear swabs of clinical suspected CSOM patients were cultured on specific cultured medium and identified the bacteria with conventional methods. Then all the identified bacteria were subjected with specific antibiotics by the Kirby–Bauer's method to know the resistance pattern of antibiotics. ESBL and MBL strains were detected by double disc diffusion test. Results: A total of 384 bacteria were isolated from 500 CSOM patients, among them 86 P. aeruginosa (22.40%), 112 Staphylococcus aureus (29.17%), 53 A. baumannii (13.80%), 32 E. aerogenes (18%), 26 C. freundii (6.77%), 24 K. oxytoca (6.25%), 23 P. vulgaris (5.99%), 18 K. pneumoniae (4.69%) and 10 P. mirabilis (2.60%) identified with conventional methods. From antibiotic disc diffusion methods 74.22% ESBL strains and 9.90% MBL strains were documented. Multidrug resistant strains of P. aeruginosa (86/384,22.40%) were more prevalent than those of S. aureus (112/384,29.17%) and other bacteria in ear discharges. Imipenem and vancomicin could control to gram negative bacteria and gram positive bacteria respectively. Conclusion: Continuous and periodic evaluation of microbiological profile and antimicrobial sensitivity pattern of bacterial is essential for optimum management of CSOM patients. Keywords: Antibiotics, Chronic suppurative otitis media, Gram negative bacteria, ESBL, MBLMahesh Chandra SahuSantosh Kumar SwainKeAi Communications Co., Ltd.articleOtorhinolaryngologyRF1-547SurgeryRD1-811ENWorld Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 5, Iss 2, Pp 88-94 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Otorhinolaryngology RF1-547 Surgery RD1-811
spellingShingle	Otorhinolaryngology RF1-547 Surgery RD1-811 Mahesh Chandra Sahu Santosh Kumar Swain Surveillance of antibiotic sensitivity pattern in chronic suppurative otitis media of an Indian teaching hospital
description	Introduction: Chronic suppurative otitis media (CSOM) is a common problem in worldwide and untreated CSOM leads to fatal complications like facial nerve paralysis, lateral sinus thrombosis, labyrinthitis, meningitis and brain abscess in developing country like India. Objective: To isolate causative bacteria and antibiotic sensitivity pattern for CSOM and to know the prevalence of extended spectrum beta lactamases (ESBL) and Metallobetalactamases (MBL) in CSOM patients. Methods: A total of 500 ear swabs of clinical suspected CSOM patients were cultured on specific cultured medium and identified the bacteria with conventional methods. Then all the identified bacteria were subjected with specific antibiotics by the Kirby–Bauer's method to know the resistance pattern of antibiotics. ESBL and MBL strains were detected by double disc diffusion test. Results: A total of 384 bacteria were isolated from 500 CSOM patients, among them 86 P. aeruginosa (22.40%), 112 Staphylococcus aureus (29.17%), 53 A. baumannii (13.80%), 32 E. aerogenes (18%), 26 C. freundii (6.77%), 24 K. oxytoca (6.25%), 23 P. vulgaris (5.99%), 18 K. pneumoniae (4.69%) and 10 P. mirabilis (2.60%) identified with conventional methods. From antibiotic disc diffusion methods 74.22% ESBL strains and 9.90% MBL strains were documented. Multidrug resistant strains of P. aeruginosa (86/384,22.40%) were more prevalent than those of S. aureus (112/384,29.17%) and other bacteria in ear discharges. Imipenem and vancomicin could control to gram negative bacteria and gram positive bacteria respectively. Conclusion: Continuous and periodic evaluation of microbiological profile and antimicrobial sensitivity pattern of bacterial is essential for optimum management of CSOM patients. Keywords: Antibiotics, Chronic suppurative otitis media, Gram negative bacteria, ESBL, MBL
format	article
author	Mahesh Chandra Sahu Santosh Kumar Swain
author_facet	Mahesh Chandra Sahu Santosh Kumar Swain
author_sort	Mahesh Chandra Sahu
title	Surveillance of antibiotic sensitivity pattern in chronic suppurative otitis media of an Indian teaching hospital
title_short	Surveillance of antibiotic sensitivity pattern in chronic suppurative otitis media of an Indian teaching hospital
title_full	Surveillance of antibiotic sensitivity pattern in chronic suppurative otitis media of an Indian teaching hospital
title_fullStr	Surveillance of antibiotic sensitivity pattern in chronic suppurative otitis media of an Indian teaching hospital
title_full_unstemmed	Surveillance of antibiotic sensitivity pattern in chronic suppurative otitis media of an Indian teaching hospital
title_sort	surveillance of antibiotic sensitivity pattern in chronic suppurative otitis media of an indian teaching hospital
publisher	KeAi Communications Co., Ltd.
publishDate	2019
url	https://doaj.org/article/80e2c4f51dea46dea00e9ccd1e90759e
work_keys_str_mv	AT maheshchandrasahu surveillanceofantibioticsensitivitypatterninchronicsuppurativeotitismediaofanindianteachinghospital AT santoshkumarswain surveillanceofantibioticsensitivitypatterninchronicsuppurativeotitismediaofanindianteachinghospital
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Surveillance of antibiotic sensitivity pattern in chronic suppurative otitis media of an Indian teaching hospital

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