$GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures$
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GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures

Size and shape of bones are important for height and body shape. Here, Styrkarsdottir et al identify 12 loci in a GWAS for bone area derived from DXA scans and show that these loci associate with other bone-related phenotypes including osteoarthritis, height, bone mineral density and risk of hip fra...

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Autores principales:	Unnur Styrkarsdottir, Olafur A. Stefansson, Kristbjorg Gunnarsdottir, Gudmar Thorleifsson, Sigrun H. Lund, Lilja Stefansdottir, Kristinn Juliusson, Arna B. Agustsdottir, Florian Zink, Gisli H. Halldorsson, Erna V. Ivarsdottir, Stefania Benonisdottir, Hakon Jonsson, Arnaldur Gylfason, Kristjan Norland, Katerina Trajanoska, Cindy G. Boer, Lorraine Southam, Jason C. S. Leung, Nelson L. S. Tang, Timothy C. Y. Kwok, Jenny S. W. Lee, Suzanne C. Ho, Inger Byrjalsen, Jacqueline R. Center, Seung Hun Lee, Jung-Min Koh, L. Stefan Lohmander, Lan T. Ho-Pham, Tuan V. Nguyen, John A. Eisman, Jean Woo, Ping-C. Leung, John Loughlin, Eleftheria Zeggini, Claus Christiansen, Fernando Rivadeneira, Joyce van Meurs, Andre G. Uitterlinden, Brynjolfur Mogensen, Helgi Jonsson, Thorvaldur Ingvarsson, Gunnar Sigurdsson, Rafn Benediktsson, Patrick Sulem, Ingileif Jonsdottir, Gisli Masson, Hilma Holm, Gudmundur L. Norddahl, Unnur Thorsteinsdottir, Daniel F. Gudbjartsson, Kari Stefansson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/80e678269bfd4ce6a62646dd799db50a
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spelling	oai:doaj.org-article:80e678269bfd4ce6a62646dd799db50a2021-12-02T16:58:05ZGWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures10.1038/s41467-019-09860-02041-1723https://doaj.org/article/80e678269bfd4ce6a62646dd799db50a2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09860-0https://doaj.org/toc/2041-1723Size and shape of bones are important for height and body shape. Here, Styrkarsdottir et al identify 12 loci in a GWAS for bone area derived from DXA scans and show that these loci associate with other bone-related phenotypes including osteoarthritis, height, bone mineral density and risk of hip fracture.Unnur StyrkarsdottirOlafur A. StefanssonKristbjorg GunnarsdottirGudmar ThorleifssonSigrun H. LundLilja StefansdottirKristinn JuliussonArna B. AgustsdottirFlorian ZinkGisli H. HalldorssonErna V. IvarsdottirStefania BenonisdottirHakon JonssonArnaldur GylfasonKristjan NorlandKaterina TrajanoskaCindy G. BoerLorraine SouthamJason C. S. LeungNelson L. S. TangTimothy C. Y. KwokJenny S. W. LeeSuzanne C. HoInger ByrjalsenJacqueline R. CenterSeung Hun LeeJung-Min KohL. Stefan LohmanderLan T. Ho-PhamTuan V. NguyenJohn A. EismanJean WooPing-C. LeungJohn LoughlinEleftheria ZegginiClaus ChristiansenFernando RivadeneiraJoyce van MeursAndre G. UitterlindenBrynjolfur MogensenHelgi JonssonThorvaldur IngvarssonGunnar SigurdssonRafn BenediktssonPatrick SulemIngileif JonsdottirGisli MassonHilma HolmGudmundur L. NorddahlUnnur ThorsteinsdottirDaniel F. GudbjartssonKari StefanssonNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Unnur Styrkarsdottir Olafur A. Stefansson Kristbjorg Gunnarsdottir Gudmar Thorleifsson Sigrun H. Lund Lilja Stefansdottir Kristinn Juliusson Arna B. Agustsdottir Florian Zink Gisli H. Halldorsson Erna V. Ivarsdottir Stefania Benonisdottir Hakon Jonsson Arnaldur Gylfason Kristjan Norland Katerina Trajanoska Cindy G. Boer Lorraine Southam Jason C. S. Leung Nelson L. S. Tang Timothy C. Y. Kwok Jenny S. W. Lee Suzanne C. Ho Inger Byrjalsen Jacqueline R. Center Seung Hun Lee Jung-Min Koh L. Stefan Lohmander Lan T. Ho-Pham Tuan V. Nguyen John A. Eisman Jean Woo Ping-C. Leung John Loughlin Eleftheria Zeggini Claus Christiansen Fernando Rivadeneira Joyce van Meurs Andre G. Uitterlinden Brynjolfur Mogensen Helgi Jonsson Thorvaldur Ingvarsson Gunnar Sigurdsson Rafn Benediktsson Patrick Sulem Ingileif Jonsdottir Gisli Masson Hilma Holm Gudmundur L. Norddahl Unnur Thorsteinsdottir Daniel F. Gudbjartsson Kari Stefansson GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures
description	Size and shape of bones are important for height and body shape. Here, Styrkarsdottir et al identify 12 loci in a GWAS for bone area derived from DXA scans and show that these loci associate with other bone-related phenotypes including osteoarthritis, height, bone mineral density and risk of hip fracture.
format	article
author	Unnur Styrkarsdottir Olafur A. Stefansson Kristbjorg Gunnarsdottir Gudmar Thorleifsson Sigrun H. Lund Lilja Stefansdottir Kristinn Juliusson Arna B. Agustsdottir Florian Zink Gisli H. Halldorsson Erna V. Ivarsdottir Stefania Benonisdottir Hakon Jonsson Arnaldur Gylfason Kristjan Norland Katerina Trajanoska Cindy G. Boer Lorraine Southam Jason C. S. Leung Nelson L. S. Tang Timothy C. Y. Kwok Jenny S. W. Lee Suzanne C. Ho Inger Byrjalsen Jacqueline R. Center Seung Hun Lee Jung-Min Koh L. Stefan Lohmander Lan T. Ho-Pham Tuan V. Nguyen John A. Eisman Jean Woo Ping-C. Leung John Loughlin Eleftheria Zeggini Claus Christiansen Fernando Rivadeneira Joyce van Meurs Andre G. Uitterlinden Brynjolfur Mogensen Helgi Jonsson Thorvaldur Ingvarsson Gunnar Sigurdsson Rafn Benediktsson Patrick Sulem Ingileif Jonsdottir Gisli Masson Hilma Holm Gudmundur L. Norddahl Unnur Thorsteinsdottir Daniel F. Gudbjartsson Kari Stefansson
author_facet	Unnur Styrkarsdottir Olafur A. Stefansson Kristbjorg Gunnarsdottir Gudmar Thorleifsson Sigrun H. Lund Lilja Stefansdottir Kristinn Juliusson Arna B. Agustsdottir Florian Zink Gisli H. Halldorsson Erna V. Ivarsdottir Stefania Benonisdottir Hakon Jonsson Arnaldur Gylfason Kristjan Norland Katerina Trajanoska Cindy G. Boer Lorraine Southam Jason C. S. Leung Nelson L. S. Tang Timothy C. Y. Kwok Jenny S. W. Lee Suzanne C. Ho Inger Byrjalsen Jacqueline R. Center Seung Hun Lee Jung-Min Koh L. Stefan Lohmander Lan T. Ho-Pham Tuan V. Nguyen John A. Eisman Jean Woo Ping-C. Leung John Loughlin Eleftheria Zeggini Claus Christiansen Fernando Rivadeneira Joyce van Meurs Andre G. Uitterlinden Brynjolfur Mogensen Helgi Jonsson Thorvaldur Ingvarsson Gunnar Sigurdsson Rafn Benediktsson Patrick Sulem Ingileif Jonsdottir Gisli Masson Hilma Holm Gudmundur L. Norddahl Unnur Thorsteinsdottir Daniel F. Gudbjartsson Kari Stefansson
author_sort	Unnur Styrkarsdottir
title	GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures
title_short	GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures
title_full	GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures
title_fullStr	GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures
title_full_unstemmed	GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures
title_sort	gwas of bone size yields twelve loci that also affect height, bmd, osteoarthritis or fractures
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/80e678269bfd4ce6a62646dd799db50a
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GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures

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