Study of the Therapeutic Effects of Chinese Herbal Decoction Combined with Glucocorticoid in Treating Primary Nephrotic Syndrome in Children

Background. To investigate the clinical effects of Chinese medicine decoction combined with glucocorticoid in treating children with primary nephrotic syndrome. Methods. A total of 70 children with pediatric nephritis nephrotic syndrome treated at Weifang People’s Hospital from January 2019 to Decem...

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Autores principales:	Xue Hou, Meihua Xu, Jie Li, Rui Li, Jinzhi Zhang, Jing Ju
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Other systems of medicine RZ201-999
Acceso en línea:	https://doaj.org/article/80e7230759d9420aa8ce4a08b3d52dfa
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spelling	oai:doaj.org-article:80e7230759d9420aa8ce4a08b3d52dfa2021-11-29T00:56:57ZStudy of the Therapeutic Effects of Chinese Herbal Decoction Combined with Glucocorticoid in Treating Primary Nephrotic Syndrome in Children1741-428810.1155/2021/4434504https://doaj.org/article/80e7230759d9420aa8ce4a08b3d52dfa2021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/4434504https://doaj.org/toc/1741-4288Background. To investigate the clinical effects of Chinese medicine decoction combined with glucocorticoid in treating children with primary nephrotic syndrome. Methods. A total of 70 children with pediatric nephritis nephrotic syndrome treated at Weifang People’s Hospital from January 2019 to December 2019 were randomly allocated to the therapy group and the control group, each with 35 cases. The control group was treated with conventional Western medicine, and the therapy group received Western medicine and Chinese medicine. After 12 weeks of treatment, the therapeutic effect of the two groups was compared. Results. After receiving the treatment, the levels of urine protein (UPro), triglyceride, and cholesterol were significantly decreased in the two groups (p<0.05), and these levels in the therapy group were much lower than those of the control group (p<0.05). However, the level of albumin (ALB) was predominantly increased in the two groups after treatment (p<0.05), and this level in the therapy group was much higher than that of the control group (p<0.05). Moreover, the immune indicators, coagulation function, and recurrence rate were noticeably improved after treatment (p<0.05), and the therapy group was better than the control group (p<0.05). Furthermore, the comparison of renal function indexes, liver function indexes, and blood routine between the two groups showed no statistical significance in the incidence of adverse reactions between the two groups (p>0.05). Conclusions. For the treatment of refractory nephrotic syndrome in children, based on conventional shock therapy, the addition of traditional Chinese medicine (Liuwei Dihuang pill decoction) remedy can significantly improve the disease symptoms in children and improve the efficacy, and the incidence of adverse reactions is low.Xue HouMeihua XuJie LiRui LiJinzhi ZhangJing JuHindawi LimitedarticleOther systems of medicineRZ201-999ENEvidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Other systems of medicine RZ201-999
spellingShingle	Other systems of medicine RZ201-999 Xue Hou Meihua Xu Jie Li Rui Li Jinzhi Zhang Jing Ju Study of the Therapeutic Effects of Chinese Herbal Decoction Combined with Glucocorticoid in Treating Primary Nephrotic Syndrome in Children
description	Background. To investigate the clinical effects of Chinese medicine decoction combined with glucocorticoid in treating children with primary nephrotic syndrome. Methods. A total of 70 children with pediatric nephritis nephrotic syndrome treated at Weifang People’s Hospital from January 2019 to December 2019 were randomly allocated to the therapy group and the control group, each with 35 cases. The control group was treated with conventional Western medicine, and the therapy group received Western medicine and Chinese medicine. After 12 weeks of treatment, the therapeutic effect of the two groups was compared. Results. After receiving the treatment, the levels of urine protein (UPro), triglyceride, and cholesterol were significantly decreased in the two groups (p<0.05), and these levels in the therapy group were much lower than those of the control group (p<0.05). However, the level of albumin (ALB) was predominantly increased in the two groups after treatment (p<0.05), and this level in the therapy group was much higher than that of the control group (p<0.05). Moreover, the immune indicators, coagulation function, and recurrence rate were noticeably improved after treatment (p<0.05), and the therapy group was better than the control group (p<0.05). Furthermore, the comparison of renal function indexes, liver function indexes, and blood routine between the two groups showed no statistical significance in the incidence of adverse reactions between the two groups (p>0.05). Conclusions. For the treatment of refractory nephrotic syndrome in children, based on conventional shock therapy, the addition of traditional Chinese medicine (Liuwei Dihuang pill decoction) remedy can significantly improve the disease symptoms in children and improve the efficacy, and the incidence of adverse reactions is low.
format	article
author	Xue Hou Meihua Xu Jie Li Rui Li Jinzhi Zhang Jing Ju
author_facet	Xue Hou Meihua Xu Jie Li Rui Li Jinzhi Zhang Jing Ju
author_sort	Xue Hou
title	Study of the Therapeutic Effects of Chinese Herbal Decoction Combined with Glucocorticoid in Treating Primary Nephrotic Syndrome in Children
title_short	Study of the Therapeutic Effects of Chinese Herbal Decoction Combined with Glucocorticoid in Treating Primary Nephrotic Syndrome in Children
title_full	Study of the Therapeutic Effects of Chinese Herbal Decoction Combined with Glucocorticoid in Treating Primary Nephrotic Syndrome in Children
title_fullStr	Study of the Therapeutic Effects of Chinese Herbal Decoction Combined with Glucocorticoid in Treating Primary Nephrotic Syndrome in Children
title_full_unstemmed	Study of the Therapeutic Effects of Chinese Herbal Decoction Combined with Glucocorticoid in Treating Primary Nephrotic Syndrome in Children
title_sort	study of the therapeutic effects of chinese herbal decoction combined with glucocorticoid in treating primary nephrotic syndrome in children
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/80e7230759d9420aa8ce4a08b3d52dfa
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Study of the Therapeutic Effects of Chinese Herbal Decoction Combined with Glucocorticoid in Treating Primary Nephrotic Syndrome in Children

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