Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma

The tumour microenvironment plays an important role in promoting glioblastoma. Here, the authors show that glioma stem cells secrete WISP1, which promotes both the survival of the stem cells and tumour-associated macrophages.

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Autores principales:	Weiwei Tao, Chengwei Chu, Wenchao Zhou, Zhi Huang, Kui Zhai, Xiaoguang Fang, Qian Huang, Aili Zhang, Xiuxing Wang, Xingjiang Yu, Haidong Huang, Qiulian Wu, Andrew E. Sloan, Jennifer S. Yu, Xiaoxia Li, George R. Stark, Jeremy N. Rich, Shideng Bao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/80ed06b6daa44b72a61177b8c8e47066
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spelling	oai:doaj.org-article:80ed06b6daa44b72a61177b8c8e470662021-12-02T16:04:12ZDual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma10.1038/s41467-020-16827-z2041-1723https://doaj.org/article/80ed06b6daa44b72a61177b8c8e470662020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16827-zhttps://doaj.org/toc/2041-1723The tumour microenvironment plays an important role in promoting glioblastoma. Here, the authors show that glioma stem cells secrete WISP1, which promotes both the survival of the stem cells and tumour-associated macrophages.Weiwei TaoChengwei ChuWenchao ZhouZhi HuangKui ZhaiXiaoguang FangQian HuangAili ZhangXiuxing WangXingjiang YuHaidong HuangQiulian WuAndrew E. SloanJennifer S. YuXiaoxia LiGeorge R. StarkJeremy N. RichShideng BaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Weiwei Tao Chengwei Chu Wenchao Zhou Zhi Huang Kui Zhai Xiaoguang Fang Qian Huang Aili Zhang Xiuxing Wang Xingjiang Yu Haidong Huang Qiulian Wu Andrew E. Sloan Jennifer S. Yu Xiaoxia Li George R. Stark Jeremy N. Rich Shideng Bao Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma
description	The tumour microenvironment plays an important role in promoting glioblastoma. Here, the authors show that glioma stem cells secrete WISP1, which promotes both the survival of the stem cells and tumour-associated macrophages.
format	article
author	Weiwei Tao Chengwei Chu Wenchao Zhou Zhi Huang Kui Zhai Xiaoguang Fang Qian Huang Aili Zhang Xiuxing Wang Xingjiang Yu Haidong Huang Qiulian Wu Andrew E. Sloan Jennifer S. Yu Xiaoxia Li George R. Stark Jeremy N. Rich Shideng Bao
author_facet	Weiwei Tao Chengwei Chu Wenchao Zhou Zhi Huang Kui Zhai Xiaoguang Fang Qian Huang Aili Zhang Xiuxing Wang Xingjiang Yu Haidong Huang Qiulian Wu Andrew E. Sloan Jennifer S. Yu Xiaoxia Li George R. Stark Jeremy N. Rich Shideng Bao
author_sort	Weiwei Tao
title	Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma
title_short	Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma
title_full	Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma
title_fullStr	Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma
title_full_unstemmed	Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma
title_sort	dual role of wisp1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/80ed06b6daa44b72a61177b8c8e47066
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Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma

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