Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma
The tumour microenvironment plays an important role in promoting glioblastoma. Here, the authors show that glioma stem cells secrete WISP1, which promotes both the survival of the stem cells and tumour-associated macrophages.
Guardado en:
Autores principales: | Weiwei Tao, Chengwei Chu, Wenchao Zhou, Zhi Huang, Kui Zhai, Xiaoguang Fang, Qian Huang, Aili Zhang, Xiuxing Wang, Xingjiang Yu, Haidong Huang, Qiulian Wu, Andrew E. Sloan, Jennifer S. Yu, Xiaoxia Li, George R. Stark, Jeremy N. Rich, Shideng Bao |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/80ed06b6daa44b72a61177b8c8e47066 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth
por: Yu Shi, et al.
Publicado: (2017) -
Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells
por: Rebeca Fernandez-Ruiz, et al.
Publicado: (2020) -
WISP-1 drives bone formation at the expense of fat formation in human perivascular stem cells
por: Carolyn A. Meyers, et al.
Publicado: (2018) -
WISP1/CCN4 inhibits adipocyte differentiation through repression of PPARγ activity
por: Nathalie Ferrand, et al.
Publicado: (2017) -
Evaluation of WISP1 as a candidate gene for bone mineral density in the Old Order Amish
por: Xing Wang, et al.
Publicado: (2018)