Own song selectivity in the songbird auditory pathway: suppression by norepinephrine.
<h4>Background</h4>Like human speech, birdsong is a learned behavior that supports species and individual recognition. Norepinephrine is a catecholamine suspected to play a role in song learning. The goal of this study was to investigate the role of norepinephrine in bird's own song...
Guardado en:
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Public Library of Science (PLoS)
2011
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/80f34ba05bfc4d178f801a484e1eccab |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:80f34ba05bfc4d178f801a484e1eccab |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:80f34ba05bfc4d178f801a484e1eccab2021-11-18T06:53:30ZOwn song selectivity in the songbird auditory pathway: suppression by norepinephrine.1932-620310.1371/journal.pone.0020131https://doaj.org/article/80f34ba05bfc4d178f801a484e1eccab2011-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21625389/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Like human speech, birdsong is a learned behavior that supports species and individual recognition. Norepinephrine is a catecholamine suspected to play a role in song learning. The goal of this study was to investigate the role of norepinephrine in bird's own song selectivity, a property thought to be important for auditory feedback processes required for song learning and maintenance.<h4>Methodology/principal findings</h4>Using functional magnetic resonance imaging, we show that injection of DSP-4, a specific noradrenergic toxin, unmasks own song selectivity in the dorsal part of NCM, a secondary auditory region.<h4>Conclusions/significance</h4>The level of norepinephrine throughout the telencephalon is known to be high in alert birds and low in sleeping birds. Our results suggest that norepinephrine activity can be further decreased, giving rise to a strong own song selective signal in dorsal NCM. This latent own song selective signal, which is only revealed under conditions of very low noradrenergic activity, might play a role in the auditory feedback and/or the integration of this feedback with the motor circuitry for vocal learning and maintenance.Colline PoirierTiny BoumansMichiel VellemaGeert De GroofThierry D CharlierMarleen VerhoyeAnnemie Van der LindenJacques BalthazartPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 6, Iss 5, p e20131 (2011) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Medicine R Science Q |
| spellingShingle |
Medicine R Science Q Colline Poirier Tiny Boumans Michiel Vellema Geert De Groof Thierry D Charlier Marleen Verhoye Annemie Van der Linden Jacques Balthazart Own song selectivity in the songbird auditory pathway: suppression by norepinephrine. |
| description |
<h4>Background</h4>Like human speech, birdsong is a learned behavior that supports species and individual recognition. Norepinephrine is a catecholamine suspected to play a role in song learning. The goal of this study was to investigate the role of norepinephrine in bird's own song selectivity, a property thought to be important for auditory feedback processes required for song learning and maintenance.<h4>Methodology/principal findings</h4>Using functional magnetic resonance imaging, we show that injection of DSP-4, a specific noradrenergic toxin, unmasks own song selectivity in the dorsal part of NCM, a secondary auditory region.<h4>Conclusions/significance</h4>The level of norepinephrine throughout the telencephalon is known to be high in alert birds and low in sleeping birds. Our results suggest that norepinephrine activity can be further decreased, giving rise to a strong own song selective signal in dorsal NCM. This latent own song selective signal, which is only revealed under conditions of very low noradrenergic activity, might play a role in the auditory feedback and/or the integration of this feedback with the motor circuitry for vocal learning and maintenance. |
| format |
article |
| author |
Colline Poirier Tiny Boumans Michiel Vellema Geert De Groof Thierry D Charlier Marleen Verhoye Annemie Van der Linden Jacques Balthazart |
| author_facet |
Colline Poirier Tiny Boumans Michiel Vellema Geert De Groof Thierry D Charlier Marleen Verhoye Annemie Van der Linden Jacques Balthazart |
| author_sort |
Colline Poirier |
| title |
Own song selectivity in the songbird auditory pathway: suppression by norepinephrine. |
| title_short |
Own song selectivity in the songbird auditory pathway: suppression by norepinephrine. |
| title_full |
Own song selectivity in the songbird auditory pathway: suppression by norepinephrine. |
| title_fullStr |
Own song selectivity in the songbird auditory pathway: suppression by norepinephrine. |
| title_full_unstemmed |
Own song selectivity in the songbird auditory pathway: suppression by norepinephrine. |
| title_sort |
own song selectivity in the songbird auditory pathway: suppression by norepinephrine. |
| publisher |
Public Library of Science (PLoS) |
| publishDate |
2011 |
| url |
https://doaj.org/article/80f34ba05bfc4d178f801a484e1eccab |
| work_keys_str_mv |
AT collinepoirier ownsongselectivityinthesongbirdauditorypathwaysuppressionbynorepinephrine AT tinyboumans ownsongselectivityinthesongbirdauditorypathwaysuppressionbynorepinephrine AT michielvellema ownsongselectivityinthesongbirdauditorypathwaysuppressionbynorepinephrine AT geertdegroof ownsongselectivityinthesongbirdauditorypathwaysuppressionbynorepinephrine AT thierrydcharlier ownsongselectivityinthesongbirdauditorypathwaysuppressionbynorepinephrine AT marleenverhoye ownsongselectivityinthesongbirdauditorypathwaysuppressionbynorepinephrine AT annemievanderlinden ownsongselectivityinthesongbirdauditorypathwaysuppressionbynorepinephrine AT jacquesbalthazart ownsongselectivityinthesongbirdauditorypathwaysuppressionbynorepinephrine |
| _version_ |
1718424239429648384 |