NAP1-RELATED PROTEIN1 and 2 negatively regulate H2A.Z abundance in chromatin in Arabidopsis

The histone variant H2A.Z is deposited by the SWR1 complex to replace H2A in Arabidopsis, but the mechanism of H2A.Z removal is unclear. Here, the authors show that NRP proteins can regulate gene expression by counteracting SWR1 and prevent excessive accumulation of H2A.Z.

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Autores principales: Yafei Wang, Zhenhui Zhong, Yaxin Zhang, Linhao Xu, Suhua Feng, Shima Rayatpisheh, James A. Wohlschlegel, Zonghua Wang, Steven E. Jacobsen, Israel Ausin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/81030512cb524031903d06aa83c3e60c
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spelling oai:doaj.org-article:81030512cb524031903d06aa83c3e60c2021-12-02T17:52:09ZNAP1-RELATED PROTEIN1 and 2 negatively regulate H2A.Z abundance in chromatin in Arabidopsis10.1038/s41467-020-16691-x2041-1723https://doaj.org/article/81030512cb524031903d06aa83c3e60c2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16691-xhttps://doaj.org/toc/2041-1723The histone variant H2A.Z is deposited by the SWR1 complex to replace H2A in Arabidopsis, but the mechanism of H2A.Z removal is unclear. Here, the authors show that NRP proteins can regulate gene expression by counteracting SWR1 and prevent excessive accumulation of H2A.Z.Yafei WangZhenhui ZhongYaxin ZhangLinhao XuSuhua FengShima RayatpishehJames A. WohlschlegelZonghua WangSteven E. JacobsenIsrael AusinNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yafei Wang
Zhenhui Zhong
Yaxin Zhang
Linhao Xu
Suhua Feng
Shima Rayatpisheh
James A. Wohlschlegel
Zonghua Wang
Steven E. Jacobsen
Israel Ausin
NAP1-RELATED PROTEIN1 and 2 negatively regulate H2A.Z abundance in chromatin in Arabidopsis
description The histone variant H2A.Z is deposited by the SWR1 complex to replace H2A in Arabidopsis, but the mechanism of H2A.Z removal is unclear. Here, the authors show that NRP proteins can regulate gene expression by counteracting SWR1 and prevent excessive accumulation of H2A.Z.
format article
author Yafei Wang
Zhenhui Zhong
Yaxin Zhang
Linhao Xu
Suhua Feng
Shima Rayatpisheh
James A. Wohlschlegel
Zonghua Wang
Steven E. Jacobsen
Israel Ausin
author_facet Yafei Wang
Zhenhui Zhong
Yaxin Zhang
Linhao Xu
Suhua Feng
Shima Rayatpisheh
James A. Wohlschlegel
Zonghua Wang
Steven E. Jacobsen
Israel Ausin
author_sort Yafei Wang
title NAP1-RELATED PROTEIN1 and 2 negatively regulate H2A.Z abundance in chromatin in Arabidopsis
title_short NAP1-RELATED PROTEIN1 and 2 negatively regulate H2A.Z abundance in chromatin in Arabidopsis
title_full NAP1-RELATED PROTEIN1 and 2 negatively regulate H2A.Z abundance in chromatin in Arabidopsis
title_fullStr NAP1-RELATED PROTEIN1 and 2 negatively regulate H2A.Z abundance in chromatin in Arabidopsis
title_full_unstemmed NAP1-RELATED PROTEIN1 and 2 negatively regulate H2A.Z abundance in chromatin in Arabidopsis
title_sort nap1-related protein1 and 2 negatively regulate h2a.z abundance in chromatin in arabidopsis
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/81030512cb524031903d06aa83c3e60c
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