EFFECT OF TRANSPLANTATION OF IMMUNOCOMPETENT CELLS TREATED WITH CAFFEINE ON THE PARAMETERS OF THE NERVOUS SYSTEM FUNCTIONAL ACTIVITY

It was demonstrated that in vitro treatment with caffeine splenocytes of mice (CBAxC57Bl / 6) F1 with a passive type of behavior in «open field» modifies the functional activity of these cells, manifested in changes in spontaneous and induced cytokine production; the intravenous injection of these c...

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Autores principales:	M. A. Knyazheva, S. L. Rizikova, T. G. Ryabicheva, E. V. Markova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2012
Materias:	caffeine immune cells exploratory behavior cytokines Science Q
Acceso en línea:	https://doaj.org/article/8103448f58304dffad7980a1f92cf7df
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spelling	oai:doaj.org-article:8103448f58304dffad7980a1f92cf7df2021-11-23T06:14:20ZEFFECT OF TRANSPLANTATION OF IMMUNOCOMPETENT CELLS TREATED WITH CAFFEINE ON THE PARAMETERS OF THE NERVOUS SYSTEM FUNCTIONAL ACTIVITY2541-94202587-9596https://doaj.org/article/8103448f58304dffad7980a1f92cf7df2012-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/936https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596It was demonstrated that in vitro treatment with caffeine splenocytes of mice (CBAxC57Bl / 6) F1 with a passive type of behavior in «open field» modifies the functional activity of these cells, manifested in changes in spontaneous and induced cytokine production; the intravenous injection of these cells is accompanied by modulation of the parameters of the motor and exploratory activity of recipients, the nature of which depends on the dose of caffeine. At the same time were shown some changes in the synthesis of cytokines by brain cells of mice-recipients. Possible mechanisms for modulating effect of transplanted immune cells on recipient's behavior were discussed.M. A. KnyazhevaS. L. RizikovaT. G. RyabichevaE. V. MarkovaScientific Сentre for Family Health and Human Reproduction Problemsarticlecaffeineimmune cellsexploratory behaviorcytokinesScienceQRUActa Biomedica Scientifica, Vol 0, Iss 3(2), Pp 284-287 (2012)
institution	DOAJ
collection	DOAJ
language	RU
topic	caffeine immune cells exploratory behavior cytokines Science Q
spellingShingle	caffeine immune cells exploratory behavior cytokines Science Q M. A. Knyazheva S. L. Rizikova T. G. Ryabicheva E. V. Markova EFFECT OF TRANSPLANTATION OF IMMUNOCOMPETENT CELLS TREATED WITH CAFFEINE ON THE PARAMETERS OF THE NERVOUS SYSTEM FUNCTIONAL ACTIVITY
description	It was demonstrated that in vitro treatment with caffeine splenocytes of mice (CBAxC57Bl / 6) F1 with a passive type of behavior in «open field» modifies the functional activity of these cells, manifested in changes in spontaneous and induced cytokine production; the intravenous injection of these cells is accompanied by modulation of the parameters of the motor and exploratory activity of recipients, the nature of which depends on the dose of caffeine. At the same time were shown some changes in the synthesis of cytokines by brain cells of mice-recipients. Possible mechanisms for modulating effect of transplanted immune cells on recipient's behavior were discussed.
format	article
author	M. A. Knyazheva S. L. Rizikova T. G. Ryabicheva E. V. Markova
author_facet	M. A. Knyazheva S. L. Rizikova T. G. Ryabicheva E. V. Markova
author_sort	M. A. Knyazheva
title	EFFECT OF TRANSPLANTATION OF IMMUNOCOMPETENT CELLS TREATED WITH CAFFEINE ON THE PARAMETERS OF THE NERVOUS SYSTEM FUNCTIONAL ACTIVITY
title_short	EFFECT OF TRANSPLANTATION OF IMMUNOCOMPETENT CELLS TREATED WITH CAFFEINE ON THE PARAMETERS OF THE NERVOUS SYSTEM FUNCTIONAL ACTIVITY
title_full	EFFECT OF TRANSPLANTATION OF IMMUNOCOMPETENT CELLS TREATED WITH CAFFEINE ON THE PARAMETERS OF THE NERVOUS SYSTEM FUNCTIONAL ACTIVITY
title_fullStr	EFFECT OF TRANSPLANTATION OF IMMUNOCOMPETENT CELLS TREATED WITH CAFFEINE ON THE PARAMETERS OF THE NERVOUS SYSTEM FUNCTIONAL ACTIVITY
title_full_unstemmed	EFFECT OF TRANSPLANTATION OF IMMUNOCOMPETENT CELLS TREATED WITH CAFFEINE ON THE PARAMETERS OF THE NERVOUS SYSTEM FUNCTIONAL ACTIVITY
title_sort	effect of transplantation of immunocompetent cells treated with caffeine on the parameters of the nervous system functional activity
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2012
url	https://doaj.org/article/8103448f58304dffad7980a1f92cf7df
work_keys_str_mv	AT maknyazheva effectoftransplantationofimmunocompetentcellstreatedwithcaffeineontheparametersofthenervoussystemfunctionalactivity AT slrizikova effectoftransplantationofimmunocompetentcellstreatedwithcaffeineontheparametersofthenervoussystemfunctionalactivity AT tgryabicheva effectoftransplantationofimmunocompetentcellstreatedwithcaffeineontheparametersofthenervoussystemfunctionalactivity AT evmarkova effectoftransplantationofimmunocompetentcellstreatedwithcaffeineontheparametersofthenervoussystemfunctionalactivity
_version_	1718417261977403392

EFFECT OF TRANSPLANTATION OF IMMUNOCOMPETENT CELLS TREATED WITH CAFFEINE ON THE PARAMETERS OF THE NERVOUS SYSTEM FUNCTIONAL ACTIVITY

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