Down-regulation of GABA(A) receptor via promiscuity with the vasoactive peptide urotensin II receptor. Potential involvement in astrocyte plasticity.

GABA(A) receptor (GABA(A)R) expression level is inversely correlated with the proliferation rate of astrocytes after stroke or during malignancy of astrocytoma, leading to the hypothesis that GABA(A)R expression/activation may work as a cell proliferation repressor. A number of vasoactive peptides e...

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Autores principales: Laurence Desrues, Thomas Lefebvre, Céline Lecointre, Marie-Thérèse Schouft, Jérôme Leprince, Vincent Compère, Fabrice Morin, François Proust, Pierrick Gandolfo, Marie-Christine Tonon, Hélène Castel
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/810f8ec5d5604b14910117823a6b5cba
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