The relationship between depression, anxiety, and cardiovascular outcomes in patients with acute coronary syndromes

Jeff C Huffman1, Christopher M Celano1, James L Januzzi21Department of Psychiatry, 2Department of Cardiology, Massachusetts General Hospital, Boston, MA USAAbstract: Depression and anxiety occur at high rates among patients suffering an acute coronary syndrome (ACS). Both depressive symptoms and anx...

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Autores principales:	Jeff C Huffman, Christopher M Celano, James L Januzzi
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/8117b283717542c89242ba1ecb3bd219
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spelling	oai:doaj.org-article:8117b283717542c89242ba1ecb3bd2192021-12-02T03:11:49ZThe relationship between depression, anxiety, and cardiovascular outcomes in patients with acute coronary syndromes1176-63281178-2021https://doaj.org/article/8117b283717542c89242ba1ecb3bd2192010-05-01T00:00:00Zhttp://www.dovepress.com/the-relationship-between-depression-anxiety-and-cardiovascular-outcome-a4375https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Jeff C Huffman1, Christopher M Celano1, James L Januzzi21Department of Psychiatry, 2Department of Cardiology, Massachusetts General Hospital, Boston, MA USAAbstract: Depression and anxiety occur at high rates among patients suffering an acute coronary syndrome (ACS). Both depressive symptoms and anxiety appear to adversely affect in-hospital and long term cardiac outcomes of post-ACS patients, independent of traditional risk factors. Despite their high prevalence and serious impact, mood and anxiety symptoms go unrecognized and untreated in most ACS patients and such symptoms (rather than being transient reactions to ACS) persist for months and beyond. The mechanisms by which depression and anxiety are linked to these negative medical outcomes are likely a combination of the effects of these conditions on inflammation, catecholamines, heart rate variability, and endothelial function, along with effects on health-promoting behavior. Fortunately, standard treatments for these disorders appear to be safe, well-tolerated and efficacious in this population; indeed, selective serotonin reuptake inhibitors may actually improve cardiac outcomes. Future research goals include gaining a better understanding of the combined effects of depression and anxiety, as well as definitive prospective studies of the impact of treatment on cardiac outcomes. Clinically, protocols that allow for efficient and systematic screening, evaluation, and treatment for depression and anxiety in cardiac patients are critical to help patients avoid the devastating effects of these illnesses on quality of life and cardiac health.Keywords: acute coronary syndrome, anxiety, anxiety disorders, depression, myocardial infarction, unstable angina Jeff C HuffmanChristopher M CelanoJames L JanuzziDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2010, Iss Issue 1, Pp 123-136 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Jeff C Huffman Christopher M Celano James L Januzzi The relationship between depression, anxiety, and cardiovascular outcomes in patients with acute coronary syndromes
description	Jeff C Huffman1, Christopher M Celano1, James L Januzzi21Department of Psychiatry, 2Department of Cardiology, Massachusetts General Hospital, Boston, MA USAAbstract: Depression and anxiety occur at high rates among patients suffering an acute coronary syndrome (ACS). Both depressive symptoms and anxiety appear to adversely affect in-hospital and long term cardiac outcomes of post-ACS patients, independent of traditional risk factors. Despite their high prevalence and serious impact, mood and anxiety symptoms go unrecognized and untreated in most ACS patients and such symptoms (rather than being transient reactions to ACS) persist for months and beyond. The mechanisms by which depression and anxiety are linked to these negative medical outcomes are likely a combination of the effects of these conditions on inflammation, catecholamines, heart rate variability, and endothelial function, along with effects on health-promoting behavior. Fortunately, standard treatments for these disorders appear to be safe, well-tolerated and efficacious in this population; indeed, selective serotonin reuptake inhibitors may actually improve cardiac outcomes. Future research goals include gaining a better understanding of the combined effects of depression and anxiety, as well as definitive prospective studies of the impact of treatment on cardiac outcomes. Clinically, protocols that allow for efficient and systematic screening, evaluation, and treatment for depression and anxiety in cardiac patients are critical to help patients avoid the devastating effects of these illnesses on quality of life and cardiac health.Keywords: acute coronary syndrome, anxiety, anxiety disorders, depression, myocardial infarction, unstable angina
format	article
author	Jeff C Huffman Christopher M Celano James L Januzzi
author_facet	Jeff C Huffman Christopher M Celano James L Januzzi
author_sort	Jeff C Huffman
title	The relationship between depression, anxiety, and cardiovascular outcomes in patients with acute coronary syndromes
title_short	The relationship between depression, anxiety, and cardiovascular outcomes in patients with acute coronary syndromes
title_full	The relationship between depression, anxiety, and cardiovascular outcomes in patients with acute coronary syndromes
title_fullStr	The relationship between depression, anxiety, and cardiovascular outcomes in patients with acute coronary syndromes
title_full_unstemmed	The relationship between depression, anxiety, and cardiovascular outcomes in patients with acute coronary syndromes
title_sort	relationship between depression, anxiety, and cardiovascular outcomes in patients with acute coronary syndromes
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/8117b283717542c89242ba1ecb3bd219
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The relationship between depression, anxiety, and cardiovascular outcomes in patients with acute coronary syndromes

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