Prolonged bacterial lag time results in small colony variants that represent a sub-population of persisters
Persisters are bacterial subpopulations that are not killed by antibiotics even though they lack genetic resistance. Here, the authors show that persisters can manifest as small colony variants in clinical infections, and arise as a result of a long lag time in stress conditions including antibiotic...
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Autores principales: | Clément Vulin, Nadja Leimer, Markus Huemer, Martin Ackermann, Annelies S. Zinkernagel |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/812279b4d2374954bb816ff97c4123c5 |
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