Context specificity of the EMT transcriptional response

It is unclear if a common EMT expression program exists. Here, the authors perform multiplexed single-cell RNA sequencing across 12 EMT time courses and 16 kinase inhibitor screens, and find that EMT transcriptional responses are context specific and EMT is not a single, linear transition.

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Detalles Bibliográficos
Autores principales: David P. Cook, Barbara C. Vanderhyden
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Q
Acceso en línea:https://doaj.org/article/8126cf3789ae47d38630c96ccbac743f
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